p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia.

p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia.

Item
http://www.wikidata.org/entity/Q41750451
The Growing Complexity of Cancer Cell Response to DNA-Damaging Agents: Caspase 3 Mediates Cell Death or Survival?p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death.Reciprocal influence of the p53 and the hypoxic pathwaysMutant, wild type, or overall p53 expression: freedom from clinical progression in tumours of astrocytic lineage.Targeting the hypoxia-inducible factor (HIF) pathway in cancer.Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes.p21(Cip1) and p27(Kip1) regulate cell cycle reentry after hypoxic stress but are not necessary for hypoxia-induced arrest.Hyperploidy induced by drugs that inhibit formation of microtubule promotes chromosome instability.p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.
P2860

p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia.

Item
http://www.wikidata.org/entity/Q41750451
description
2000 nî lūn-bûn
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2000年の論文
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name
p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia.
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type
label
p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia.
@en
prefLabel
p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921
P356
P1433
P1476
p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia.
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921