Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism.
about
Engineered biosynthesis of regioselectively modified aromatic polyketides using bimodular polyketide synthasesInhibition Kinetics and Emodin Cocrystal Structure of a Type II Polyketide Ketoreductase † , ‡Structural and Biochemical Characterization of ZhuI Aromatase/Cyclase from the R1128 Polyketide PathwayEvolution of polyketide synthases in bacteriaNon-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloidsCloning and characterization of the ravidomycin and chrysomycin biosynthetic gene clustersStructural enzymology of polyketide synthases.Cyclization of aromatic polyketides from bacteria and fungiCloning, sequencing, heterologous expression, and mechanistic analysis of A-74528 biosynthesisBiosynthesis of polyketides in heterologous hostsCloning and heterologous expression of three type II PKS gene clusters from Streptomyces bottropensis.Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unitStreptomyces genetics: a genomic perspective.The enzymology of combinatorial biosynthesis.Engineered biosynthesis of the antiparasitic agent frenolicin B and rationally designed analogs in a heterologous hostCharacterization of the two-component monooxygenase system AlnT/AlnH reveals early timing of quinone formation in alnumycin biosynthesisStructural and functional analysis of two di-domain aromatase/cyclases from type II polyketide synthasesType II polyketide synthases: gaining a deeper insight into enzymatic teamwork.Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli.Biosynthesis of aromatic polyketides in bacteria.Cloning and Heterologous Expression of a Large-sized Natural Product Biosynthetic Gene Cluster in Streptomyces SpeciesConvergent strategies in biosynthesis.The structural role of the carrier protein--active controller or passive carrier.Expression of biosynthetic gene clusters in heterologous hosts for natural product production and combinatorial biosynthesis.The role of transcription in heterologous expression of polyketides in bacterial hosts.Neocarzinostatin naphthoate synthase: an unique iterative type I PKS from neocarzinostatin producer Streptomyces carzinostaticus.Structure and Biosynthesis of Isatropolones, Bioactive Amine-Scavenging Fluorescent Natural Products from Streptomyces Gö66.Gene cluster on pAO1 of Arthrobacter nicotinovorans involved in degradation of the plant alkaloid nicotine: cloning, purification, and characterization of 2,6-dihydroxypyridine 3-hydroxylase.The biochemical basis for stereochemical control in polyketide biosynthesis.Characterization of FabG and FabI of the Streptomyces coelicolor dissociated fatty acid synthase.The complete gene cluster of the antitumor agent gilvocarcin V and its implication for the biosynthesis of the gilvocarcins.Cloning and characterization of a new polyketide synthase gene cluster in Streptomyces aureofaciens CCM 3239.Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.In vivo and in vitro analysis of the hedamycin polyketide synthase.Biosynthesis of cervimycin C, an aromatic polyketide antibiotic bearing an unusual dimethylmalonyl moiety.Tandemly duplicated acyl carrier proteins, which increase polyketide antibiotic production, can apparently function either in parallel or in series.Dissection of the neocarazostatin: a C4 alkyl side chain biosynthesis by in vitro reconstitution.Involvement of the Baeyer-Villiger Monooxygenase IfnQ in the Biosynthesis of Isofuranonaphthoquinone Scaffold of JBIR-76 and -77.Huanglongmycin A-C, Cytotoxic Polyketides Biosynthesized by a Putative Type II Polyketide Synthase From Streptomyces sp. CB09001.
P2860
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P2860
Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Cloning, nucleotide sequence, ...... an unusual priming mechanism.
@en
type
label
Cloning, nucleotide sequence, ...... an unusual priming mechanism.
@en
prefLabel
Cloning, nucleotide sequence, ...... an unusual priming mechanism.
@en
P2093
P2860
P356
P1476
Cloning, nucleotide sequence, ...... an unusual priming mechanism.
@en
P2093
P2860
P304
33443-33448
P356
10.1074/JBC.M006766200
P407
P577
2000-10-01T00:00:00Z