Role of Cl- in electrogenic Na+-coupled cotransporters GAT1 and SGLT1.
about
Substrates regulate gamma-aminobutyric acid transporters in a syntaxin 1A-dependent manner.The interaction of the gamma-aminobutyric acid transporter GAT-1 with the neurotransmitter is selectively impaired by sulfhydryl modification of a conformationally sensitive cysteine residue engineered into extracellular loop IVTransmembrane domain I of the gamma-aminobutyric acid transporter GAT-1 plays a crucial role in the transition between cation leak and transport modesThe aqueous accessibility in the external half of transmembrane domain I of the GABA transporter GAT-1 Is modulated by its ligandsLocalization and Function of GABA Transporters GAT-1 and GAT-3 in the Basal GangliaCommon mechanisms of inhibition for the Na+/glucose (hSGLT1) and Na+/Cl-/GABA (hGAT1) cotransportersCharacterization of the rat Na+/nucleoside cotransporter 2 and transport of nucleoside-derived drugs using electrophysiological methodsRole of the conserved glutamine 291 in the rat gamma-aminobutyric acid transporter rGAT-1Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study analyzing the neurotransmitter/Na+ symporter family.Rapid substrate-induced charge movements of the GABA transporter GAT1.GABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRETSubstrate-dependent proton antiport in neurotransmitter:sodium symporters.Ionic currents in the human serotonin transporter reveal inconsistencies in the alternating access hypothesisMechanism of anion selectivity and stoichiometry of the Na+/I- symporter (NIS).Dynamics of forward and reverse transport by the glial glycine transporter, glyt1b.GATMD: γ-aminobutyric acid transporter mutagenesis database.Turnover rate of the gamma-aminobutyric acid transporter GAT1.Novel properties of a mouse gamma-aminobutyric acid transporter (GAT4).Why glycine transporters have different stoichiometries.Sodium translocation by the iminoglycinuria associated imino transporter (SLC6A20).Ion transporter NKCC1, modulator of neurogenesis in murine olfactory neurons.Bridging the gap between structure and kinetics of human SGLT1.Electrogenic glutamate transporters in the CNS: molecular mechanism, pre-steady-state kinetics, and their impact on synaptic signaling.Conformational dynamics of hSGLT1 during Na+/glucose cotransportThe solute carrier 6 family of transportersPerturbation analysis of the voltage-sensitive conformational changes of the Na+/glucose cotransporter.Functional consequences of sulfhydryl modification of the γ-aminobutyric acid transporter 1 at a single solvent-exposed cysteine residue.Inhibition of Activity of GABA Transporter GAT1 by δ-Opioid Receptor.Characterization of human SLC4A10 as an electroneutral Na/HCO3 cotransporter (NBCn2) with Cl- self-exchange activity.Modular structure of sodium-coupled bicarbonate transportersInhibitors of the gamma-aminobutyric acid transporter 1 (GAT1) do not reveal a channel mode of conductionStructure, function, and plasticity of GABA transporters.The sodium/multivitamin transporter: a multipotent system with therapeutic implications.An Extra Amino Acid Residue in Transmembrane Domain 10 of the γ-Aminobutyric Acid (GABA) Transporter GAT-1 Is Required for Efficient Ion-coupled Transport.Electrogenic Binding of Intracellular Cations Defines a Kinetic Decision Point in the Transport Cycle of the Human Serotonin Transporter.Currents in response to rapid concentration jumps of amphetamine uncover novel aspects of human dopamine transporter function.Cloning and characterization of a functional human gamma-aminobutyric acid (GABA) transporter, human GAT-2.Contribution of astrocytic glutamate and GABA uptake to corticostriatal information processing.Cl⁻ homeodynamics in gap junction-coupled astrocytic networks on activation of GABAergic synapsesConformational basis for the Li(+)-induced leak current in the rat gamma-aminobutyric acid (GABA) transporter-1.
P2860
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P2860
Role of Cl- in electrogenic Na+-coupled cotransporters GAT1 and SGLT1.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Role of Cl- in electrogenic Na+-coupled cotransporters GAT1 and SGLT1.
@en
type
label
Role of Cl- in electrogenic Na+-coupled cotransporters GAT1 and SGLT1.
@en
prefLabel
Role of Cl- in electrogenic Na+-coupled cotransporters GAT1 and SGLT1.
@en
P2093
P2860
P921
P356
P1476
Role of Cl- in electrogenic Na+-coupled cotransporters GAT1 and SGLT1.
@en
P2093
P2860
P304
37414-37422
P356
10.1074/JBC.M007241200
P407
P577
2000-12-01T00:00:00Z