Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function.
about
Inflammasome/IL-1β Responses to Streptococcal PathogensDangerous Liaisons: Caspase-11 and Reactive Oxygen Species Crosstalk in Pathogen EliminationReactive oxygen species at the crossroads of inflammasome and inflammationInsights into phagocytosis-coupled activation of pattern recognition receptors and inflammasomesMechanisms of inflammasome activation: recent advances and novel insightsNatural Compounds as Regulators of NLRP3 Inflammasome-Mediated IL-1β ProductionNeutrophils: Between host defence, immune modulation, and tissue injuryFunctional genomics identifies negative regulatory nodes controlling phagocyte oxidative burstLocalization and functionality of the inflammasome in neutrophilsSelective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistanceDefective mitophagy driven by dysregulation of rheb and KIF5B contributes to mitochondrial reactive oxygen species (ROS)-induced nod-like receptor 3 (NLRP3) dependent proinflammatory response and aggravates lipotoxicityGrowth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death.Gene expression profiles in granuloma tissue reveal novel diagnostic markers in sarcoidosis.Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome.Oxidative stress and hepatic Nox proteins in chronic hepatitis C and hepatocellular carcinoma.Intravascular immunity as a key to systemic vasculitis: a work in progress, gaining momentum.Caspase-1/ASC inflammasome-mediated activation of IL-1β-ROS-NF-κB pathway for control of Trypanosoma cruzi replication and survival is dispensable in NLRP3-/- macrophages.Passive immunization with anti-glucosaminidase monoclonal antibodies protects mice from implant-associated osteomyelitis by mediating opsonophagocytosis of Staphylococcus aureus megaclusters.Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivoStaphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular.Staphylococcus aureus Strain USA300 Perturbs Acquisition of Lysosomal Enzymes and Requires Phagosomal Acidification for Survival inside Macrophages.The Endoplasmic Reticulum Stress Sensor Inositol-Requiring Enzyme 1α Augments Bacterial Killing through Sustained Oxidant Production.Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance.Inability to sustain intraphagolysosomal killing of Staphylococcus aureus predisposes to bacterial persistence in macrophagesMitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense.Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling.Ugonin U stimulates NLRP3 inflammasome activation and enhances inflammasome-mediated pathogen clearanceDifferential roles of caspase-1 and caspase-11 in infection and inflammation.The signaling pathway of NADPH oxidase and its role in glomerular diseases.Caspases as the key effectors of inflammatory responses against bacterial infection.Scaling of immune responses against intracellular bacterial infection.Perception of self: distinguishing autoimmunity from autoinflammation.An In Vitro Model for the Study of the Macrophage Response Upon Trichophyton rubrum Challenge.Inflammasome Complexes: Emerging Mechanisms and Effector Functions.Alternative functions for the multifarious inflammasome.Necroptosis induced by RIPK3 requires MLKL but not Drp1.Inflammasomes and intestinal inflammation.Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases.TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles).
P2860
Q26779173-F83C6EC5-0CFF-4028-92D4-EF378FD68A1CQ26783077-D51D9F8A-BE46-40C8-AAE6-AAAD8D037693Q26830685-0AD40C0C-15B5-4E30-BDEF-C6CC20C17D00Q26865044-66CA54EC-293C-44D8-A6D2-257FB00D8E4BQ27005760-A5551E47-C278-4BC6-B42C-BF7B61007BD5Q28072287-BE39AB30-13D0-4D28-88CC-56282C1E369AQ28087227-2B656A6C-9A09-46C7-933E-21B3B36EB0AEQ28265365-F276BB65-E4F6-4142-8FAB-BDCAEE546959Q28305418-FE65ED8A-5F95-444F-91D2-58802E76495FQ28539668-C025FD6F-CEC3-4EDA-96F1-F7E90119116DQ28575583-80456841-D1AD-47D0-89DB-3B3A258CD253Q30827681-E9B4E4A4-8B88-4486-9304-09F6EDBC76A3Q33723775-1C4F641A-5003-42C5-A036-DB9F5582B19AQ33821118-9F089B0B-E56A-47C6-8FD0-E86BE014A20EQ33904328-DB2911E8-78E9-43FB-89CE-EF0CA8D801E9Q34377832-4ABB005A-688E-487C-88D3-A419707C65B6Q34456390-9FBA71A6-BFE2-4E36-AB28-4195B9A6DC3CQ34522708-A63CEEEF-6B58-415B-B4F0-FB24DCCB67E4Q35206149-4055C672-8604-48EC-926A-76BF7A3B26ECQ35556626-DDEC6F30-D39B-4922-94FB-BB6A51B23AF7Q35662239-FD04D1F4-EE3C-4EB1-BF48-9BDC5F6A5BD1Q35821714-6049CF1F-BE07-4C4C-BBC0-81E9F802FB90Q35851420-E23C36F6-393C-46C1-A81B-27BC75192502Q36388033-AD7C20FF-61CF-46F8-B88E-768C2496F75CQ36652082-CDB9E1B5-A0D6-4408-B1EE-500DE0A632D9Q37197479-3483C9DB-6079-4CB7-960D-C6B4026D55BBQ37211555-EA91E492-1C8E-4847-A249-764FD4F793E2Q37543814-3F31AE33-69F4-439F-9047-48804F0AEA0BQ37721559-02ADA41B-217B-429C-B4FA-CDACB5F05B7AQ38155196-A1E1B093-98D0-4732-B7CB-DEDE5B1656B4Q38230622-CF972BC5-E374-41AB-9C63-427092CAD633Q38250060-ECE6A78F-80AE-4F58-B683-9096D8D8C4D8Q38474054-7478C3B7-E30E-4EB7-A507-C73624358637Q38741177-10C7E452-91E9-4BE8-8E91-3C3B7A698AEDQ38827667-FD008B82-0400-4894-8D0A-8D695541AE1DQ38952803-97A60692-C837-4D04-8673-412E3F4BB150Q39020252-124C5B09-86F7-4304-866D-4A54293E25A7Q39237282-9D9B22EA-50F6-4E0D-8EE4-EC424DA67213Q39277467-F96EFFBB-88E4-40B8-B611-A97DDB9D8D84Q39524777-E968B042-EE4D-48DF-A3D0-E99E2648E664
P2860
Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Activation of caspase-1 by the ...... to control phagosome function.
@en
type
label
Activation of caspase-1 by the ...... to control phagosome function.
@en
prefLabel
Activation of caspase-1 by the ...... to control phagosome function.
@en
P2093
P2860
P356
P1433
P1476
Activation of caspase-1 by the ...... to control phagosome function.
@en
P2093
Anna Sokolovska
Antoine Tanne
Christine E Becker
Katherine A Fitzgerald
Lynda M Stuart
Matthew Brudner
Nicholas Paquette
Sivapriya K Vanaja
Vijay A K Rathinam
W K Eddie Ip
P2860
P304
P356
10.1038/NI.2595
P407
P577
2013-05-05T00:00:00Z