Hyaluronate degradation as an alternative mechanism for proteoglycan release from cartilage during interleukin-1beta-stimulated catabolism.
about
Hyaluronan - a functional and structural sweet spot in the tissue microenvironmentMatrix metalloproteinases are not essential for aggrecan turnover during normal skeletal growth and development.CS lyases: structure, activity, and applications in analysis and the treatment of diseasesInternalization of aggrecan G1 domain neoepitope ITEGE in chondrocytes requires CD44Aggrecanolysis and in vitro matrix degradation in the immature bovine meniscus: mechanisms and functional implications.Noninvasive estimation of liver fibrosis and response to interferon therapy by a serum fibrogenesis marker, YKL-40, in patients with HCV-associated liver disease.ADAMTS-5 deficiency does not block aggrecanolysis at preferred cleavage sites in the chondroitin sulfate-rich region of aggrecan.Extracellular processing of the cartilage proteoglycan aggregate and its effect on CD44-mediated internalization of hyaluronanInvolvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilageBlocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repairExperimentally induced cartilage degeneration treated by pulsed electromagnetic field stimulation; an in vitro study on bovine cartilage.YKL-40 genetic polymorphisms and the risk of liver disease progression in patients with advanced fibrosis due to chronic hepatitis CEvidence for lysosomal exocytosis and release of aggrecan-degrading hydrolases from hypertrophic chondrocytes, in vitro and in vivo.Selective and non-selective metalloproteinase inhibitors reduce IL-1-induced cartilage degradation and loss of mechanical properties.4-Methylumbelliferone Diminishes Catabolically Activated Articular Chondrocytes and Cartilage Explants via a Mechanism Independent of Hyaluronan Inhibition.Serum YKL-40 as a marker of liver fibrosis in patients with non-alcoholic fatty liver disease.Hyaluronic acid fragments enhance the inflammatory and catabolic response in human intervertebral disc cells through modulation of toll-like receptor 2 signalling pathways.Hyaluronic acid regulates a key redox control factor Nrf2 via phosphorylation of Akt in bovine articular chondrocytes.Oncostatin M in combination with tumour necrosis factor {alpha} induces a chondrocyte membrane associated aggrecanase that is distinct from ADAMTS aggrecanase-1 or -2.Distinguishing aggrecan loss from aggrecan proteolysis in ADAMTS-4 and ADAMTS-5 single and double deficient mice.Aggrecan turnover in human intervertebral disc as determined by the racemization of aspartic acid.The pericellular hyaluronan of articular chondrocytes.Serum YKL-40 as a biomarker for liver fibrosis in chronic hepatitis B patients with normal and mildly elevated ALT.
P2860
Q28081088-2797AF90-F0FE-42E9-9AF2-70B49A7E0FF2Q33724459-98E1766F-47FC-4432-9207-EFEB3AE5E5A1Q33965779-F89511CA-7715-479E-8884-D802F216431AQ34285507-7700B3A5-ADF7-4E7A-BF6E-AC4BB704CEE4Q34413245-123AFC68-E572-41DA-B77A-457D2CFB4176Q34605692-2ADC3F38-C932-4E8A-9CBB-52C93404E7B8Q34606492-4CA011C6-1DEF-44CE-BB7A-1317EBD5B1B6Q35351732-4C1A85E9-F511-4616-8A67-52DF73EFF869Q35645792-796DC8B0-D63E-46F5-800A-8F5ECBFE2E69Q35785741-A7B4F216-85CC-448A-BCDC-4ADF57E007C7Q35813016-AEA3C3DE-FFAE-48C7-8B56-DC522E9E87D3Q35823055-47DBC87F-0D5A-4B24-B935-6C97DCF651C5Q36432069-8DE4FC2B-9168-437E-8D1C-704820EE0D34Q36688890-1E66529F-607C-44E4-8228-DE36E9579163Q37065986-9ACFE45B-C1F4-4821-838D-385659288324Q37339883-9D204C7C-93BC-41BE-B223-B6A68E05E6E7Q37690081-FBCE1837-7A4E-4DA8-8314-0B1E95EC7459Q42079163-25F073A8-141B-49D8-9052-BF279DDCF8E2Q43049411-E3520C64-A53D-4EE4-B6D2-869E17FCA1EEQ46949433-B2002D59-3608-47E8-8AB7-FDB56E3F4022Q46990448-D4E95F90-6CC2-4C5F-B94A-CB42137C31F7Q50097155-65959684-356F-4D7D-A476-719769A98CC3Q52619982-4AA06BAA-C690-470C-BD16-07ACD167A5AD
P2860
Hyaluronate degradation as an alternative mechanism for proteoglycan release from cartilage during interleukin-1beta-stimulated catabolism.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Hyaluronate degradation as an ...... n-1beta-stimulated catabolism.
@en
type
label
Hyaluronate degradation as an ...... n-1beta-stimulated catabolism.
@en
prefLabel
Hyaluronate degradation as an ...... n-1beta-stimulated catabolism.
@en
P2093
P2860
P1433
P1476
Hyaluronate degradation as an ...... n-1beta-stimulated catabolism.
@en
P2093
Anneliese D Recklies
John S Mort
Peter J Roughley
Robert Sztrolovics
P2860
P304
P356
10.1042/0264-6021:3620473
P407
P577
2002-03-01T00:00:00Z