The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition - Wikidata - wikimedia - TriplyDB

The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition

The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition

http://www.wikidata.org/entity/Q41822328

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The Dual Function of Reactive Oxygen/Nitrogen Species in Bioenergetics and Cell Death: The Role of ATP Synthase Excitation-contraction coupling of human induced pluripotent stem cell-derived cardiomyocytes Calcium signaling as a mediator of cell energy demand and a trigger to cell death The EF-Hand Ca2+ Binding Protein MICU Choreographs Mitochondrial Ca2+ Dynamics in Arabidopsis MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability.Expression of mRNA Encoding Mcu and Other Mitochondrial Calcium Regulatory Genes Depends on Cell Type, Neuronal Subtype, and Ca2+ Signaling The growing importance of mitochondrial calcium in health and disease.Real-Time Fluorescence Measurements of ROS and [Ca2+] in Ischemic / Reperfused Rat Hearts: Detectable Increases Occur only after Mitochondrial Pore Opening and Are Attenuated by Ischemic Preconditioning.MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration.Novel targets for mitochondrial medicine.A cardiac mitochondrial cAMP signaling pathway regulates calcium accumulation, permeability transition and cell death The mitochondrial Ca2+ uniporter: regulation by auxiliary subunits and signal transduction pathways.MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload.PTPIP51 regulates mouse cardiac ischemia/reperfusion through mediating the mitochondria-SR junction.The Mitochondrial Voltage-Dependent Anion Channel 1, Ca2+ Transport, Apoptosis, and Their Regulation.Small Interfering RNA Targeting Mitochondrial Calcium Uniporter Improves Cardiomyocyte Cell Viability in Hypoxia/Reoxygenation Injury by Reducing Calcium Overload.The In Vivo Biology of the Mitochondrial Calcium Uniporter.Mitochondrial Ca2+ and regulation of the permeability transition pore.Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes.The mitochondrial calcium uniporter in the heart: energetics and beyond.CaMKII is a nodal signal for multiple programmed cell death pathways in heart.Crosstalk between calcium and reactive oxygen species signaling in cancer.Sarcoplasmic reticulum-mitochondria communication in cardiovascular pathophysiology.Calcium Transport and Signaling in Mitochondria.The role of succinate and ROS in reperfusion injury - A critical appraisal.Altered Mitochondrial Metabolism and Mechanosensation in the Failing Heart: Focus on Intracellular Calcium Signaling.Structure, Activity Regulation, and Role of the Mitochondrial Calcium Uniporter in Health and Disease.Dysregulation of Mitochondrial Bioenergetics and Quality Control by HIV-1 Tat in Cardiomyocytes.DS16570511 is a small-molecule inhibitor of the mitochondrial calcium uniporter.MICU1 protects against myocardial ischemia/reperfusion injury and its control by the importer receptor Tom70 The Mitochondrial Ca2+ Uniporter: Structure, Function, and Pharmacology.Mitochondrial pathways to cardiac recovery: TFAM.Mitochondrial Ca(2+) uptake controls actin cytoskeleton dynamics during cell migration.CMT-linked loss-of-function mutations in GDAP1 impair store-operated Ca2+ entry-stimulated respiration.Mg(2+) differentially regulates two modes of mitochondrial Ca(2+) uptake in isolated cardiac mitochondria: implications for mitochondrial Ca(2+) sequestration.Global ablation of the mitochondrial calcium uniporter increases glycolysis in cortical neurons subjected to energetic stressors.Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter.Strategic Positioning and Biased Activity of the Mitochondrial Calcium Uniporter in Cardiac Muscle.Cardiac Ryanodine Receptor (Ryr2)-mediated Calcium Signals Specifically Promote Glucose Oxidation via Pyruvate Dehydrogenase

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The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition

http://www.wikidata.org/entity/Q41822328

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2015年论文

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The Mitochondrial Calcium Unip ...... ulates Permeability Transition

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The Mitochondrial Calcium Unip ...... ulates Permeability Transition

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The Mitochondrial Calcium Unip ...... ulates Permeability Transition

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J.CELREP.2015.06.017

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The Mitochondrial Calcium Unip ...... ulates Permeability Transition

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Ancai Yuan

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Erhe Gao

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Jianliang Song

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Jonathan P Lambert

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Joseph Y Cheung

http://www.w3.org/2001/XMLSchema#string

Mohit Jain

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Muniswamy Madesh

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Polina Gross

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Steven R Houser

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Timothy S Luongo

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P2860

NCLX is an essential component of mitochondrial Na+/Ca2+ exchange

MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice.

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

Molecular cloning of the cDNA of mouse mitochondrial NADP-dependent isocitrate dehydrogenase and the expression of the gene during lymphocyte activation

MCU encodes the pore conducting mitochondrial calcium currents.

Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses

Genome-wide RNAi screen identifies Letm1 as a mitochondrial Ca2+/H+ antiporter.

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1

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12

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Santhanam Shanmughapriya

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279457883

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