Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1. - Wikidata - wikimedia - TriplyDB

Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1.

Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1.

http://www.wikidata.org/entity/Q41824937

about

The adaptor protein Grb2 is not essential for the establishment of the glomerular filtration barrier Trans-interaction of nephrin and Neph1/Neph3 induces cell adhesion that associates with decreased tyrosine phosphorylation of nephrin SIRPα interacts with nephrin at the podocyte slit diaphragm Direct regulation of nephrin tyrosine phosphorylation by Nck adaptor proteins.Role of dynamin, synaptojanin, and endophilin in podocyte foot processes.Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance.Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture Nephrin regulates lamellipodia formation by assembling a protein complex that includes Ship2, filamin and lamellipodin Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease.The Accumulation of VEGFA in the Glomerular Basement Membrane and Its Relationship with Podocyte Injury and Proteinuria in Alport Syndrome.DNA methylation changes between relapse and remission of minimal change nephrotic syndrome Shp2 Associates with and Enhances Nephrin Tyrosine Phosphorylation and Is Necessary for Foot Process Spreading in Mouse Models of Podocyte Injury.Nephrin Contributes to Insulin Secretion and Affects Mammalian Target of Rapamycin Signaling Independently of Insulin Receptor Neph1 regulates steady-state surface expression of Slo1 Ca(2+)-activated K(+) channels: different effects in embryonic neurons and podocytes Endothelin receptor A-specific stimulation of glomerular inflammation and injury in a streptozotocin-induced rat model of diabetes Slit diaphragm protein Neph1 and its signaling: a novel therapeutic target for protection of podocytes against glomerular injury Anion exchanger 1 in red blood cells and kidney: Band 3's in a pod.Tyrosine kinase signaling in kidney glomerular podocytes.The podocyte cytoskeleton--key to a functioning glomerulus in health and disease.The podocyte slit diaphragm--from a thin grey line to a complex signalling hub.Functions of the podocyte proteins nephrin and Neph3 and the transcriptional regulation of their genes.An update: the role of Nephrin inside and outside the kidney.Podocyte-actin dynamics in health and disease.Regulation of Nephrin Phosphorylation in Diabetes and Chronic Kidney Injury.Altered nephrin and podoplanin distribution is associated with disturbed polarity protein PARD-3 and PARD-6 expressions in podocytes from preeclampsia.CIN85/RukL is a novel binding partner of nephrin and podocin and mediates slit diaphragm turnover in podocytes Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture.Calcium mediates glomerular filtration through calcineurin and mTORC2/Akt signaling.Tyrosine phosphorylation-dependent activation of TRPC6 regulated by PLC-γ1 and nephrin: effect of mutations associated with focal segmental glomerulosclerosis.Is the antiproteinuric effect of cyclosporine a independent of its immunosuppressive function in T cells?Glomerular proteins related to slit diaphragm and matrix adhesion in the foot processes are highly tyrosine phosphorylated in the normal rat kidney.LMX1B mutation with residual transcriptional activity as a cause of isolated glomerulopathy.PI(4;5)P2 is hydrolysed to I(1;4;5)P3 and DAG by tethered PLC[1] at the plasma membrane Altered expression of Crb2 in podocytes expands a variation of CRB2 mutations in steroid-resistant nephrotic syndrome.Nephrin expression in adult rodent central nervous system and its interaction with glutamate receptors.Nephrin Signaling in the Podocyte: An Updated View of Signal Regulation at the Slit Diaphragm and Beyond.Proteinuric Kidney Diseases: A Podocyte's Slit Diaphragm and Cytoskeleton Approach

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P2860

Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1.

http://www.wikidata.org/entity/Q41824937

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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2009年论文

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2009年论文

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name

Phosphorylation of Nephrin Tri ...... n of Phospholipase C-{gamma}1.

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Phosphorylation of Nephrin Tri ...... n of Phospholipase C-{gamma}1.

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Phosphorylation of Nephrin Tri ...... n of Phospholipase C-{gamma}1.

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Journal of Biological Chemistry

P1476

Phosphorylation of Nephrin Tri ...... n of Phospholipase C-{gamma}1.

@en

P2093

Hidetaka Kosako

http://www.w3.org/2001/XMLSchema#string

Hidetake Kurihara

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Ikuroh Ohsawa

http://www.w3.org/2001/XMLSchema#string

Seisuke Hattori

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Shigeo Ohta

http://www.w3.org/2001/XMLSchema#string

Takashi Igarashi

http://www.w3.org/2001/XMLSchema#string

Takashi Sekine

http://www.w3.org/2001/XMLSchema#string

Tohru Tezuka

http://www.w3.org/2001/XMLSchema#string

Yutaka Harita

http://www.w3.org/2001/XMLSchema#string

P2860

Phospholipase Cgamma1 controls surface expression of TRPC3 through an intermolecular PH domain

Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes

Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible

Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN

PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A

Fyn binds to and phosphorylates the kidney slit diaphragm component Nephrin

Phospholipase C-gamma1 is required for the activation of store-operated Ca2+ channels in liver cells

Phospholipase C-gamma is required for agonist-induced Ca2+ entry

The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death

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8951-8962

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10.1074/JBC.M806851200

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13

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284

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2009-01-29T00:00:00Z

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19179337

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phosphorylation

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2659252

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