A highly conserved motif at the COOH terminus dictates endoplasmic reticulum exit and cell surface expression of NKCC2.
about
A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycinMolecular regulation of NKCC2 in the thick ascending limbCommon noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expressionRare mutations in renal sodium and potassium transporter genes exhibit impaired transport function.Secretory carrier membrane protein 2 regulates exocytic insertion of NKCC2 into the cell membrane.Rare mutations in the human Na-K-Cl cotransporter (NKCC2) associated with lower blood pressure exhibit impaired processing and transport function.Exonic mutations in the SLC12A3 gene cause exon skipping and premature termination in Gitelman syndrome.The thiazide-sensitive NaCl cotransporter is targeted for chaperone-dependent endoplasmic reticulum-associated degradation.OS9 Protein Interacts with Na-K-2Cl Co-transporter (NKCC2) and Targets Its Immature Form for the Endoplasmic Reticulum-associated Degradation Pathway.Impact of Hybrid and Complex N-Glycans on Cell Surface Targeting of the Endogenous Chloride Cotransporter Slc12a2.Real-time monitoring of NKCC2 endocytosis by total internal reflection fluorescence (TIRF) microscopy.The N-terminal basolateral targeting signal unlikely acts alone in the differential trafficking of membrane transporters in MDCK cells.Vesicle-associated Membrane Protein 3 (VAMP3) Mediates Constitutive Trafficking of the Renal Co-transporter NKCC2 in Thick Ascending Limbs: ROLE IN RENAL FUNCTION AND BLOOD PRESSURE.Functional expression of the Na-K-2Cl cotransporter NKCC2 in mammalian cells fails to confirm the dominant-negative effect of the AF splice variant.Annexin A2 mediates apical trafficking of renal Na⁺-K⁺-2Cl⁻ cotransporter.The transcriptome of the Didelphis virginiana opossum kidney OK proximal tubule cell line.Multiple evolutionarily conserved Di-leucine like motifs in the carboxyl terminus control the anterograde trafficking of NKCC2.Plasma Membrane Targeting of Endogenous NKCC2 in COS7 Cells Bypasses Functional Golgi Cisternae and Complex N-Glycosylation.Localization and trafficking of an isoform of the AtPRA1 family to the Golgi apparatus depend on both N- and C-terminal sequence motifs.Processing and stability of type IIc sodium-dependent phosphate cotransporter mutations in patients with hereditary hypophosphatemic rickets with hypercalciuria.Conflict of interests: multiple signal peptides with diverging goals.
P2860
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P2860
A highly conserved motif at the COOH terminus dictates endoplasmic reticulum exit and cell surface expression of NKCC2.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
A highly conserved motif at th ...... l surface expression of NKCC2.
@en
type
label
A highly conserved motif at th ...... l surface expression of NKCC2.
@en
prefLabel
A highly conserved motif at th ...... l surface expression of NKCC2.
@en
P2093
P2860
P356
P1476
A highly conserved motif at th ...... l surface expression of NKCC2.
@en
P2093
David Mordasini
Kamel Laghmani
Nadia Defontaine
Nancy Zaarour
Sylvie Demaretz
P2860
P304
21752-21764
P356
10.1074/JBC.M109.000679
P407
P577
2009-06-17T00:00:00Z