Ecto-nucleoside triphosphate diphosphohydrolase 1 (E-NTPDase1/CD39) regulates neutrophil chemotaxis by hydrolyzing released ATP to adenosine.
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The environment of regulatory T cell biology: cytokines, metabolites, and the microbiomeLack of glucose recycling between endoplasmic reticulum and cytoplasm underlies cellular dysfunction in glucose-6-phosphatase-beta-deficient neutrophils in a congenital neutropenia syndromeRegulation of neutrophil function by adenosine.CD73 and CD39 ectonucleotidases in T cell differentiation: Beyond immunosuppressionPurinergic signaling in inflammatory cells: P2 receptor expression, functional effects, and modulation of inflammatory responsesEctonucleotidases in tumor cells and tumor-associated immune cells: an overviewmTOR and differential activation of mitochondria orchestrate neutrophil chemotaxisTh1/Th17 cell induction and corresponding reduction in ATP consumption following vaccination with the novel Mycobacterium tuberculosis vaccine MVA85AAdenosine-A3 receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes.Adenosine arrests breast cancer cell motility by A3 receptor stimulation.Streptococcus pneumoniae nasopharyngeal colonization induces type I interferons and interferon-induced gene expression.Cellular mechanisms of tissue fibrosis. 6. Purinergic signaling and response in fibroblasts and tissue fibrosisImmune cell regulation by autocrine purinergic signalling.Ticlopidine in its prodrug form is a selective inhibitor of human NTPDase1CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in miceMitochondria regulate neutrophil activation by generating ATP for autocrine purinergic signalingPurinergic signaling: a fundamental mechanism in neutrophil activation.CD39 modulates hematopoietic stem cell recruitment and promotes liver regeneration in mice and humans after partial hepatectomy.NTPDase1 governs P2X7-dependent functions in murine macrophagesP2X7 integrates PI3K/AKT and AMPK-PRAS40-mTOR signaling pathways to mediate tumor cell death.Liver damage and systemic inflammatory responses are exacerbated by the genetic deletion of CD39 in total hepatic ischemiaEctonucleotide triphosphate diphosphohydrolase-1 (CD39) mediates resistance to occlusive arterial thrombus formation after vascular injury in mice.The UDP-sugar-sensing P2Y(14) receptor promotes Rho-mediated signaling and chemotaxis in human neutrophils.The adenosine generating enzymes CD39/CD73 control microglial processes ramification in the mouse brain.Ectonucleotidases in solid organ and allogeneic hematopoietic cell transplantationThe roles of purinergic signaling during gastrointestinal inflammation.CD39 and CD73 in immunity and inflammation.Hydrolysis of extracellular ATP by ectonucleoside triphosphate diphosphohydrolase (ENTPD) establishes the set point for fibrotic activity of cardiac fibroblasts.Activation of critical, host-induced, metabolic and stress pathways marks neutrophil entry into cystic fibrosis lungs.Pannexin 1 channels link chemoattractant receptor signaling to local excitation and global inhibition responses at the front and back of polarized neutrophils.UDP-glucose promotes neutrophil recruitment in the lung.Extracellular nucleotides as negative modulators of immunity.Attenuated allergic airway inflammation in Cd39 null mice.Age-Appropriate Functions and Dysfunctions of the Neonatal Neutrophil.Purinergic signaling: a novel mechanism in immune surveillance.Ectonucleotidases as regulators of purinergic signaling in thrombosis, inflammation, and immunity.New insights regarding the regulation of chemotaxis by nucleotides, adenosine, and their receptors.CD39: Interface between vascular thrombosis and inflammation.Purinergic signalling and immune cells.Extracellular adenosine generation in the regulation of pro-inflammatory responses and pathogen colonization.
P2860
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P2860
Ecto-nucleoside triphosphate diphosphohydrolase 1 (E-NTPDase1/CD39) regulates neutrophil chemotaxis by hydrolyzing released ATP to adenosine.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Ecto-nucleoside triphosphate d ...... ing released ATP to adenosine.
@en
type
label
Ecto-nucleoside triphosphate d ...... ing released ATP to adenosine.
@en
prefLabel
Ecto-nucleoside triphosphate d ...... ing released ATP to adenosine.
@en
P2093
P2860
P356
P1476
Ecto-nucleoside triphosphate d ...... ing released ATP to adenosine.
@en
P2093
Guido Beldi
Paul A Insel
Ross Corriden
Simon C Robson
Wolfgang G Junger
Yoshiaki Inoue
P2860
P304
28480-28486
P356
10.1074/JBC.M800039200
P407
P577
2008-08-18T00:00:00Z