Functional identification of ligands for a catalytic metal ion in group I introns
about
Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1RNA catalyses nuclear pre-mRNA splicingCalcium inhibition of ribonuclease H1 two-metal ion catalysisDesign and Experimental Evolution of trans-Splicing Group I Intron Ribozymes.Structure-function analysis from the outside in: long-range tertiary contacts in RNA exhibit distinct catalytic roles.An active site rearrangement within the Tetrahymena group I ribozyme releases nonproductive interactions and allows formation of catalytic interactions.Thermodynamic evidence for negative charge stabilization by a catalytic metal ion within an RNA active siteIdentification of catalytic metal ion ligands in ribozymes.Synthesis, properties, and applications of oligonucleotides containing an RNA dinucleotide phosphorothiolate linkage.A rearrangement of the guanosine-binding site establishes an extended network of functional interactions in the Tetrahymena group I ribozyme active site.The structure of a nucleolytic ribozyme that employs a catalytic metal ion.Metal binding and substrate positioning by evolutionarily invariant U6 sequences in catalytically active protein-free snRNAs.Metal-ion rescue revisited: biochemical detection of site-bound metal ions important for RNA folding.Tightening of active site interactions en route to the transition state revealed by single-atom substitution in the guanosine-binding site of the Tetrahymena group I ribozyme.Thio effects and an unconventional metal ion rescue in the genomic hepatitis delta virus ribozyme.Mechanisms of RNA catalysis.Inner-Sphere Coordination of Divalent Metal Ion with Nucleobase in Catalytic RNA.Understanding catalysis of phosphate-transfer reactions by the large ribozymes.
P2860
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P2860
Functional identification of ligands for a catalytic metal ion in group I introns
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Functional identification of ligands for a catalytic metal ion in group I introns
@en
type
label
Functional identification of ligands for a catalytic metal ion in group I introns
@en
prefLabel
Functional identification of ligands for a catalytic metal ion in group I introns
@en
P2093
P2860
P356
P1433
P1476
Functional identification of ligands for a catalytic metal ion in group I introns
@en
P2093
Daniel Herschlag
Joseph A Piccirilli
Jungjoon K Lee
Marcello Forconi
P2860
P304
P356
10.1021/BI800519A
P407
P577
2008-06-03T00:00:00Z