Leishmania major lacking arginase (ARG) are auxotrophic for polyamines but retain infectivity to susceptible BALB/c mice
about
Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infectionsResveratrol is active against Leishmania amazonensis: in vitro effect of its association with Amphotericin BFirst evidence of intraclonal genetic exchange in trypanosomatids using two Leishmania infantum fluorescent transgenic clonesInfection with arginase-deficient Leishmania major reveals a parasite number-dependent and cytokine-independent regulation of host cellular arginase activity and disease pathogenesis.Modulation of the arginase pathway in the context of microbial pathogenesis: a metabolic enzyme moonlighting as an immune modulatorGenetically modified organisms and visceral leishmaniasisUpregulation of colonic luminal polyamines produced by intestinal microbiota delays senescence in miceLeishmania amazonensis arginase compartmentalization in the glycosome is important for parasite infectivity.Inhibition profile of Leishmania mexicana arginase reveals differences with human arginase I.Spermidine synthase is required for virulence of Leishmania donovani.Deprivation of L-Arginine Induces Oxidative Stress Mediated Apoptosis in Leishmania donovani Promastigotes: Contribution of the Polyamine PathwayTranscriptional Profiling of Coxiella burnetii Reveals Extensive Cell Wall Remodeling in the Small Cell Variant Developmental Form.Differential protein abundance in promastigotes of nitric oxide-sensitive and resistant Leishmania chagasi strains.Crystal structures of Leishmania mexicana arginase complexed with α,α-disubstituted boronic amino-acid inhibitors.Mechanisms of immune evasion in leishmaniasisParasite-derived arginase influences secondary anti-Leishmania immunity by regulating programmed cell death-1-mediated CD4+ T cell exhaustion.TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection.Arginase Is Essential for Survival of Leishmania donovani Promastigotes but Not Intracellular Amastigotes.Central carbon metabolism of Leishmania parasites.Arginase activity in pathogenic and non-pathogenic species of Leishmania parasitesPolyamine-trypanothione pathway: an update.Novel selective inhibitor of Leishmania (Leishmania) amazonensis arginase.Arginase Inhibitors: A Rational Approach Over One Century.Continual renewal and replication of persistent Leishmania major parasites in concomitantly immune hosts.l-Arginine Uptake by Cationic Amino Acid Transporter Promotes Intra-Macrophage Survival of Leishmania donovani by Enhancing Arginase-Mediated Polyamine Synthesis.L-arginine availability and arginase activity: Characterization of amino acid permease 3 in Leishmania amazonensis.Multi-analytical platform metabolomic approach to study miltefosine mechanism of action and resistance in Leishmania.Arginase expression modulates nitric oxide production in Leishmania (Leishmania) amazonensis.Arginine and Polyamines Fate in Leishmania Infection.Expression of IL-10-triggered STAT3-dependent IL-4Rα is required for induction of arginase 1 in visceral leishmaniasis.Leishmania Hijacks Myeloid Cells for Immune Escape.Bioactive polyamine production by a novel hybrid system comprising multiple indigenous gut bacterial strategies.
P2860
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P2860
Leishmania major lacking arginase (ARG) are auxotrophic for polyamines but retain infectivity to susceptible BALB/c mice
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Leishmania major lacking argin ...... ity to susceptible BALB/c mice
@en
type
label
Leishmania major lacking argin ...... ity to susceptible BALB/c mice
@en
prefLabel
Leishmania major lacking argin ...... ity to susceptible BALB/c mice
@en
P2093
P2860
P921
P1476
Leishmania major lacking argin ...... ity to susceptible BALB/c mice
@en
P2093
Melissa Showalter
Rafael Balaña-Fouce
Suzanne Hickerson
P2860
P356
10.1016/J.MOLBIOPARA.2009.01.001
P577
2009-01-20T00:00:00Z