Targeting hepatic glucokinase in type 2 diabetes: weighing the benefits and risks.

Targeting hepatic glucokinase in type 2 diabetes: weighing the benefits and risks.

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http://www.wikidata.org/entity/Q41866371
Small molecule glucokinase activators disturb lipid homeostasis and induce fatty liver in rodents: a warning for therapeutic applications in humansMolecular docking studies of (4Z, 12Z)-cyclopentadeca-4, 12-dienone from Grewia hirsuta with some targets related to type 2 diabetesGlucokinase links Krüppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver diseaseThe relative importance of kinetic mechanisms and variable enzyme abundances for the regulation of hepatic glucose metabolism--insights from mathematical modeling.Metabolite profiling reveals normal metabolic control in carriers of mutations in the glucokinase gene (MODY2)Effects of a glucokinase activator on hepatic intermediary metabolism: study with 13C-isotopomer-based metabolomics.S 50131 and S 51434, two novel small molecule glucokinase activators, lack chronic efficacy despite potent acute antihyperglycaemic activity in diabetic mice.Structural Variations of Human Glucokinase Glu256Lys in MODY2 Condition Using Molecular Dynamics Study.Increased risk of insulin resistance in rat offsprings exposed prenatally to white rice.The molecular mechanisms of liver and islets of Langerhans toxicity by benzene and its metabolite hydroquinone in vivo and in vitro.Safety, pharmacokinetics and pharmacodynamics of multiple-ascending doses of the novel glucokinase activator AZD1656 in patients with type 2 diabetes mellitus.Krüppel-Like Factors in Metabolic Homeostasis and Cardiometabolic Disease.The role of FGF21 in type 1 diabetes and its complications.
P2860

Targeting hepatic glucokinase in type 2 diabetes: weighing the benefits and risks.

Item
http://www.wikidata.org/entity/Q41866371
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Targeting hepatic glucokinase in type 2 diabetes: weighing the benefits and risks.
@en
type
label
Targeting hepatic glucokinase in type 2 diabetes: weighing the benefits and risks.
@en
prefLabel
Targeting hepatic glucokinase in type 2 diabetes: weighing the benefits and risks.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Targeting hepatic glucokinase in type 2 diabetes: weighing the benefits and risks.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932