Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers.
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Ion Channels and Oxidative Stress as a Potential Link for the Diagnosis or Treatment of Liver DiseasesJanus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domainsMouse models of diet-induced nonalcoholic steatohepatitis reproduce the heterogeneity of the human disease.Autophagosome-lysosome fusion is independent of V-ATPase-mediated acidification.Blocking Nuclear Factor-Kappa B Protects against Diet-Induced Hepatic Steatosis and Insulin Resistance in MiceCalcium Homeostasis and Organelle Function in the Pathogenesis of Obesity and Diabetes.Drosophila Gyf/GRB10 interacting GYF protein is an autophagy regulator that controls neuron and muscle homeostasis.Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cellsAmiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomyNanodrug Formed by Coassembly of Dual Anticancer Drugs to Inhibit Cancer Cell Drug Resistance.Regulation of Liver Metabolism by Autophagy.KCa3.1 mediates dysfunction of tubular autophagy in diabetic kidneys via PI3k/Akt/mTOR signaling pathwaysRegulation of cardiomyocyte autophagy by calcium.Sexual dimorphism in activation of placental autophagy in obese women with evidence for fetal programming from a placenta-specific mouse model.Calpain 2-mediated autophagy defect increases susceptibility of fatty livers to ischemia-reperfusion injury.Paeoniflorin protects diabetic mice against myocardial ischemic injury via the transient receptor potential vanilloid 1/calcitonin gene-related peptide pathway.Spautin-1 Ameliorates Acute Pancreatitis via Inhibiting Impaired Autophagy and Alleviating Calcium Overload.The hypertension drug, verapamil, activates Nrf2 by promoting p62-dependent autophagic Keap1 degradation and prevents acetaminophen-induced cytotoxicity.Boosting autophagy in the diabetic heart: a translational perspective.High fat diet disrupts endoplasmic reticulum calcium homeostasis in the rat liver.Autophagy and Obesity-Related Lung Disease.Chronic Calcium Channel Inhibitor Verapamil Antagonizes TNF-α-Mediated Inflammatory Reaction and Protects Against Inflammatory Arthritis in Mice.Clinical implications of understanding the association between oxidative stress and pediatric NAFLD.Autophagy in the liver: functions in health and disease.Autophagy and Human Neurodegenerative Diseases-A Fly's Perspective.Function of Autophagy in Nonalcoholic Fatty Liver DiseaseA new mechanism of lipotoxicity: Calcium channel blockers as a treatment for nonalcoholic steatohepatitis?Chemical chaperone 4-phenyl butyric acid (4-PBA) reduces hepatocellular lipid accumulation and lipotoxicity through induction of autophagy.Ion channels in the regulation of autophagy.Lipotoxicity induces hepatic protein inclusions through TBK1-mediated p62/SQSTM1 phosphorylation.Reduced Endoplasmic Reticulum Stress-Mediated Autophagy Is Required for Leptin Alleviating Inflammation in Adipose Tissue.Increased intracellular Ca2+ concentrations prevent membrane localization of PH domains through the formation of Ca2+-phosphoinositides.Metabolic Disorders and Cancer: Hepatocyte Store-Operated Ca2+ Channels in Nonalcoholic Fatty Liver Disease.Multifaceted Roles of GSK-3 in Cancer and Autophagy-Related Diseases.Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice.Autophagy Dysregulation and Obesity-Associated Pathologies.Non-alcoholic steatohepatitis pathogenesis: sublethal hepatocyte injury as a driver of liver inflammation.Increased expression of sterol regulatory element binding protein‑2 alleviates autophagic dysfunction in NAFLD.miR199a-5p inhibits hepatic insulin sensitivity via suppression of ATG14-mediated autophagy.A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes.
P2860
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P2860
Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Pharmacological correction of ...... sing calcium channel blockers.
@en
type
label
Pharmacological correction of ...... sing calcium channel blockers.
@en
prefLabel
Pharmacological correction of ...... sing calcium channel blockers.
@en
P2093
P2860
P356
P1476
Pharmacological correction of ...... sing calcium channel blockers.
@en
P2093
Haeli Park
Hwan-Woo Park
Ian A Semple
Insook Jang
Jeong Sig Kim
Jun Hee Lee
Jung-Jae Kim
Myungjin Kim
Seung-Hyun Ro
P2860
P2888
P356
10.1038/NCOMMS5834
P407
P577
2014-09-05T00:00:00Z
P5875
P6179
1034657557