The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity.
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Genes and Pathways Involved in Adult Onset Disorders Featuring Muscle Mitochondrial DNA InstabilityCell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative diseaseNovel mitochondrial targets for neuroprotectionMitochondria in traumatic brain injury and mitochondrial-targeted multipotential therapeutic strategiesWhat is the function of mitochondrial networks? A theoretical assessment of hypotheses and proposal for future researchOPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demandNeuronal hypoxia disrupts mitochondrial fusionSex differences in mitochondrial (dys)function: Implications for neuroprotectionMitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic CardiomyopathyA calcineurin docking motif (LXVP) in dynamin-related protein 1 contributes to mitochondrial fragmentation and ischemic neuronal injury.Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity.Mitochondrial disorders and the eye.Inhibition of calpain reduces oxidative stress and attenuates endothelial dysfunction in diabetes.The effects of NAD+ on apoptotic neuronal death and mitochondrial biogenesis and function after glutamate excitotoxicity.Mitochondrial fission augments capsaicin-induced axonal degenerationIncreased mitochondrial fission and volume density by blocking glutamate excitotoxicity protect glaucomatous optic nerve head astrocytes.A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics.Implications of mitochondrial dynamics on neurodegeneration and on hypothalamic dysfunction.Carboxylic Acid Fullerene (C60) Derivatives Attenuated Neuroinflammatory Responses by Modulating Mitochondrial Dynamics.Deletion of capn4 Protects the Heart Against Endotoxemic Injury by Preventing ATP Synthase Disruption and Inhibiting Mitochondrial Superoxide GenerationA novel algorithm identifies stress-induced alterations in mitochondrial connectivity and inner membrane structure from confocal images.Cellular alterations in human traumatic brain injury: changes in mitochondrial morphology reflect regional levels of injury severity.Mitochondrial morphology transitions and functions: implications for retrograde signaling?Altered Mitochondrial Dynamics and TBI Pathophysiology.Mitochondrial energy metabolism and redox signaling in brain aging and neurodegenerationAcidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival.Gold nanoparticles enhance TRAIL sensitivity through Drp1-mediated apoptotic and autophagic mitochondrial fission in NSCLC cellsAberrant regulation and function of Src family tyrosine kinases: their potential contributions to glutamate-induced neurotoxicity.Less than perfect divorces: dysregulated mitochondrial fission and neurodegeneration.Mitochondrial fusion proteins and human diseases.Fusion or Fission: The Destiny of Mitochondria In Traumatic Brain Injury of Different Severities.Restoration of Opa1-long isoform inhibits retinal injury-induced neurodegeneration.Mitochondrial dynamics modulate the expression of pro-inflammatory mediators in microglial cells.Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex I deficiency.Dynamic comparisons of high-resolution expression profiles highlighting mitochondria-related genes between in vivo and in vitro fertilized early mouse embryos.Parkin overexpression protects retinal ganglion cells against glutamate excitotoxicity.NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease.Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease.Mitochondrial fusion/fission, transport and autophagy in Parkinson's disease: when mitochondria get nasty.CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death.
P2860
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P2860
The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
The mitochondrial inner membra ...... ival following excitotoxicity.
@en
type
label
The mitochondrial inner membra ...... ival following excitotoxicity.
@en
prefLabel
The mitochondrial inner membra ...... ival following excitotoxicity.
@en
P2093
P2860
P356
P1476
The mitochondrial inner membra ...... vival following excitotoxicity
@en
P2093
Arezu Jahani-Asl
Jason G MacLaurin
Karine Pilon-Larose
Ruth S Slack
William Xu
P2860
P304
P356
10.1074/JBC.M110.167155
P407
P577
2010-11-01T00:00:00Z