Pyrimidine-based tricyclic molecules as potent and orally efficacious inhibitors of wee1 kinase.

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Pyrimidine-based tricyclic molecules as potent and orally efficacious inhibitors of wee1 kinase.

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2014 nî lūn-bûn

@nan

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

2014年论文

@zh

2014年论文

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name

Pyrimidine-based tricyclic mol ...... ous inhibitors of wee1 kinase.

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Item

label

Pyrimidine-based tricyclic mol ...... ous inhibitors of wee1 kinase.

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prefLabel

Pyrimidine-based tricyclic mol ...... ous inhibitors of wee1 kinase.

@en

P1476

Pyrimidine-based tricyclic mol ...... ous inhibitors of wee1 kinase.

@en

P2093

Alan S Florjancic

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Alexander R Shoemaker

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Amanda M Olson

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David Maag

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Debra C Ferguson

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Donald J Osterling

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Eric F Johnson

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Fritz G Buchanan

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Kenneth D Bromberg

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Loren M Lasko

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P2860

Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases

Death by releasing the breaks: CHK1 inhibitors as cancer therapeutics

Integrated functional, gene expression and genomic analysis for the identification of cancer targets

Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase

High expression of Wee1 is associated with poor disease-free survival in malignant melanoma: potential for targeted therapy

Drosophila Wee1 kinase regulates Cdk1 and mitotic entry during embryogenesis.

Wee1 kinase as a target for cancer therapy.

WEE1 inhibition and genomic instability in cancer.

Discovery of gene expression-based pharmacodynamic biomarker for a p53 context-specific anti-tumor drug Wee1 inhibitor.

In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma

P304

58-62

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P31

scholarly article

P356

10.1021/ML5002745

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Trevor M Penning

P577

2014-08-06T00:00:00Z

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P698

25589931

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P932

4291713

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