about
The Novel PKCθ from Benchtop to ClinicPharmacological Inhibition of PKCθ Counteracts Muscle Disease in a Mouse Model of Duchenne Muscular Dystrophy.T cell Receptor Signal Transduction in T lymphocytes.The yin and yang of protein kinase C-theta (PKCθ): a novel drug target for selective immunosuppression.PKC-ѳ is dispensable for OX40L-induced TCR-independent Treg proliferation but contributes by enabling IL-2 production from effector T-cells.Regulation of immune system cell functions by protein kinase C.SRC1 promotes Th17 differentiation by overriding Foxp3 suppression to stimulate RORγt activity in a PKC-θ-dependent manner.Targeting early PKCθ-dependent T-cell infiltration of dystrophic muscle reduces disease severity in a mouse model of muscular dystrophy.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Intervention of PKC-θ as an immunosuppressive regimen.
@en
type
label
Intervention of PKC-θ as an immunosuppressive regimen.
@en
prefLabel
Intervention of PKC-θ as an immunosuppressive regimen.
@en
P2860
P356
P1476
Intervention of PKC-θ as an immunosuppressive regimen.
@en
P2093
Zuoming Sun
P2860
P356
10.3389/FIMMU.2012.00225
P577
2012-08-02T00:00:00Z