Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcription
about
CTCF: master weaver of the genomeThe complex transcription regulatory landscape of our genome: control in three dimensionsCTCF: the protein, the binding partners, the binding sites and their chromatin loopsChromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elementsMaintenance of long-range DNA interactions after inhibition of ongoing RNA polymerase II transcription.Adventitious changes in long-range gene expression caused by polymorphic structural variation and promoter competitionFetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene clusterCell type specificity of chromatin organization mediated by CTCF and cohesin.Topology of mammalian developmental enhancers and their regulatory landscapes.Insulated Neighborhoods: Structural and Functional Units of Mammalian Gene Control.In the loop: long range chromatin interactions and gene regulation.Enhancers: the abundance and function of regulatory sequences beyond promoters.Cohesin mediates chromatin interactions that regulate mammalian β-globin expressionDistinctive signatures of histone methylation in transcribed coding and noncoding human beta-globin sequencesFunctional validation of mouse tyrosinase non-coding regulatory DNA elements by CRISPR-Cas9-mediated mutagenesisLong-Range Chromatin InteractionsThe hypersensitive sites of the murine β-globin locus control region act independently to affect nuclear localization and transcriptional elongation.Deletion of the Scl +19 enhancer increases the blood stem cell compartment without affecting the formation of mature blood lineages.CTCF-mediated transcriptional regulation through cell type-specific chromosome organization in the β-globin locus.Replication-timing boundaries facilitate cell-type and species-specific regulation of a rearranged human chromosome in mouse.Enhancer blocking activity of the insulator at H19-ICR is independent of chromatin barrier establishment.Epigenetics of beta-globin gene regulationβ-Globin cis-elements determine differential nuclear targeting through epigenetic modifications.A spectrum of gene regulatory phenomena at mammalian beta-globin gene loci.Gene insulation. Part II: natural strategies in vertebrates.Chromatin insulator elements: establishing barriers to set heterochromatin boundaries.Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization.Molecular Diagnosis of Thalassemias and Hemoglobinopathies: An ACLPS Critical Review.DT40 knock-out and knock-in studies determine the regions necessary and sufficient for transcription and epigenetic conversion of the chicken Ig-β gene.Loss of Major DNase I Hypersensitive Sites in Duplicated β-globin Gene Cluster Incompletely Silences HBB Gene Expression.Impaired in vitro erythropoiesis following deletion of the Scl (Tal1) +40 enhancer is largely compensated for in vivo despite a significant reduction in expressionCooperativeness of the higher chromatin structure of the beta-globin locus revealed by the deletion mutations of DNase I hypersensitive site 3 of the LCR.Beta-globin active chromatin Hub formation in differentiating erythroid cells and in p45 NF-E2 knock-out mice.Graphene oxide regulates cox2 in human embryonic kidney 293T cells via epigenetic mechanisms: dynamic chromosomal interactions.
P2860
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P2860
Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcription
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Flanking HS-62.5 and 3' HS1, a ...... for beta-globin transcription
@en
type
label
Flanking HS-62.5 and 3' HS1, a ...... for beta-globin transcription
@en
prefLabel
Flanking HS-62.5 and 3' HS1, a ...... for beta-globin transcription
@en
P2093
P2860
P1433
P1476
Flanking HS-62.5 and 3' HS1, a ...... for beta-globin transcription
@en
P2093
Agnes Telling
M A Bender
Mark Groudine
Michael Bulger
Rachel Byron
Tobias Ragoczy
P2860
P304
P356
10.1182/BLOOD-2006-04-014431
P407
P577
2006-04-27T00:00:00Z