Deregulation of the phosphatase, PP2A is a common event in breast cancer, predicting sensitivity to FTY720.
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The emerging role of FTY720 (Fingolimod) in cancer treatmentProtein Phosphatases Involved in Regulating Mitosis: Facts and HypothesesPP2A: The Wolf in Sheep's Clothing?Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage.PP2A inhibition determines poor outcome and doxorubicin resistance in early breast cancer and its activation shows promising therapeutic effectsActionable pharmacogenetic markers for prediction and prognosis in breast cancer.The phosphorylated prodrug FTY720 is a histone deacetylase inhibitor that reactivates ERα expression and enhances hormonal therapy for breast cancer.Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2.Quantitative Proteomic Approach for MicroRNA Target Prediction Based on 18O/16O Labeling.Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): an oncoprotein with many hands.OP449 inhibits breast cancer growth without adverse metabolic effects.Role of "oncogenic nexus" of CIP2A in breast oncogenesis: how does it work?Reprogramming the oncogenic response: SET protein as a potential therapeutic target in cancer.Inhibition of protein methylesterase 1 decreased cancerous phenotypes in endometrial adenocarcinoma cell lines and xenograft tumor models.Activation of the Tumor Suppressor PP2A Emerges as a Potential Therapeutic Strategy for Treating Prostate Cancer.Deregulation of the protein phosphatase 2A, PP2A in cancer: complexity and therapeutic options.Cip2a promotes cell cycle progression in triple-negative breast cancer cells by regulating the expression and nuclear export of p27Kip1.(DEAD)-box RNA helicase 3 modulates NF-κB signal pathway by controlling the phosphorylation of PP2A-C subunit.PP2A as the Main Node of Therapeutic Strategies and Resistance Reversal in Triple-Negative Breast Cancer.Functional importance of PP2A regulatory subunit loss in breast cancer.CIP2A expression predicts recurrences of tamoxifen-treated breast cancer.PP2A deactivation is a common event in oral cancer and reactivation by FTY720 shows promising therapeutic potential.Estradiol suppresses phosphorylation of ERα serine 167 through upregulation of PP2A in breast cancer cells.MicroRNA-652 induces NED in LNCaP and EMT in PC3 prostate cancer cells.
P2860
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P2860
Deregulation of the phosphatase, PP2A is a common event in breast cancer, predicting sensitivity to FTY720.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Deregulation of the phosphatas ...... dicting sensitivity to FTY720.
@en
type
label
Deregulation of the phosphatas ...... dicting sensitivity to FTY720.
@en
prefLabel
Deregulation of the phosphatas ...... dicting sensitivity to FTY720.
@en
P2093
P2860
P356
P1433
P1476
Deregulation of the phosphatas ...... dicting sensitivity to FTY720.
@en
P2093
Anthony G Fenech
Christian Saliba
Nigel Borg
Vanessa Petroni
P2860
P2888
P356
10.1186/1878-5085-5-3
P577
2014-01-25T00:00:00Z
P5875
P6179
1052574773