Pathogenesis of mucous cell metaplasia in a murine asthma model. - Wikidata - wikimedia - TriplyDB

Pathogenesis of mucous cell metaplasia in a murine asthma model.

Pathogenesis of mucous cell metaplasia in a murine asthma model.

http://www.wikidata.org/entity/Q41925077

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Goblet cells are derived from a FOXJ1-expressing progenitor in a human airway epithelium The pattern of methacholine responsiveness in mice is dependent on antigen challenge dose Derivation and validation of murine histologic alterations resembling asthma, with two proposed histologic grade parameters.Airway mucus function and dysfunction.Inhaled salmeterol and/or fluticasone alters structure/function in a murine model of allergic airways disease.Aldose reductase inhibition prevents metaplasia of airway epithelial cells.Effects of ultrafine particles-induced oxidative stress on Clara cells in allergic lung inflammation.Epithelial repair mechanisms in the lung Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals.Analysis of airway secretions in a model of sulfur dioxide induced chronic obstructive pulmonary disease (COPD).Proceedings of the 2014 National Toxicology Program Satellite Symposium Murine CLCA5 is uniquely expressed in distinct niches of airway epithelial cells.Differentiated cultures of primary hamster tracheal airway epithelial cells Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.Lung development and repair: contribution of the ciliated lineage.Chronic lung injury by constitutive expression of activation-induced cytidine deaminase leads to focal mucous cell metaplasia and cancer.Airway mucus: From production to secretion.Roles of apoptosis in airway epithelia.Immunogenetic programs for viral induction of mucous cell metaplasia Airway epithelial stem cells and the pathophysiology of chronic obstructive pulmonary disease.Ciliated cells of pseudostratified airway epithelium do not become mucous cells after ovalbumin challenge.Maintenance and repair of the bronchiolar epithelium.Ultrastructural changes of airway in murine models of allergy and diet-induced metabolic syndrome.T cells suppress memory-dependent rapid mucous cell metaplasia in mouse airways.Advances in mucous cell metaplasia: a plug for mucus as a therapeutic focus in chronic airway disease.Modeling asthma in mice: what have we learned about the airway epithelium?Cellular and molecular mechanisms of goblet cell metaplasia in the respiratory airways.Quantitative microscopy of the lung: a problem-based approach. Part 2: stereological parameters and study designs in various diseases of the respiratory tract.Distal airways are protected from goblet cell metaplasia by diminished expression of IL-13 signalling components.Chemokine-mediated angiogenesis: an essential link in the evolution of airway fibrosis?Nuclear factor-kappaB activation in airway epithelium induces inflammation and hyperresponsiveness.The role of atoh1 in mucous cell metaplasia Extensive goblet cell metaplasia of the peripheral lung may harbor precancerous molecular changes: comparison of two cases.Loss of pro-apoptotic Bim promotes accumulation of pulmonary T lymphocytes and enhances allergen-induced goblet cell metaplasia.Budesonide effects on Clara cell under normal and allergic inflammatory condition.Assessment of intracellular mucin content in vivo Neurotoxic, inflammatory, and mucosecretory responses in the nasal airways of mice repeatedly exposed to the macrocyclic trichothecene mycotoxin roridin A: dose-response and persistence of injury.Time-dependent airway epithelial and inflammatory cell responses induced by influenza virus A/PR/8/34 in C57BL/6 mice.Restoration of the normal Clara cell phenotype after chronic allergic inflammation.Epithelial cell distribution and abundance in rhesus monkey airways during postnatal lung growth and development.

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P2860

Pathogenesis of mucous cell metaplasia in a murine asthma model.

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The American Journal of Pathology

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Pathogenesis of mucous cell metaplasia in a murine asthma model.

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Dallas M Hyde

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Edward S Schelegle

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J Rachel Reader

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Jeffrey S Tepper

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Juergen W Pfeiffer

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Lei F Putney

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Melinda C Aldrich

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P2860

Allergic asthma induced in rhesus monkeys by house dust mite (Dermatophagoides farinae)

Objective quantitative analysis of eosinophils and bronchial epithelial cells in induced sputum by laser scanning cytometry.

Three-dimensional mapping of ozone-induced acute cytotoxicity in tracheobronchial airways of isolated perfused rat lung.

Modulation of allergic inflammation in mice deficient in TNF receptors.

Eosinophil recruitment into the respiratory epithelium following antigenic challenge in hyper-IgE mice is accompanied by interleukin 5-dependent bronchial hyperresponsiveness.

The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma.

The distal airways: are they important in asthma?

Mechanisms of eosinophil-associated inflammation.

Asthma. From bronchoconstriction to airways inflammation and remodeling.

Bronchial epithelium as a key regulator of airway allergen sensitization and remodeling in asthma.

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