In vitro activities of quinine and other antimalarials and pfnhe polymorphisms in Plasmodium isolates from Kenya
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Challenges of drug-resistant malariaAntimalarial Drug Resistance: Literature Review and Activities and Findings of the ICEMR NetworkThe interplay between drug resistance and fitness in malaria parasitesGlobal analysis of Plasmodium falciparum Na(+)/H(+) exchanger (pfnhe-1) allele polymorphism and its usefulness as a marker of in vitro resistance to quinineA HECT ubiquitin-protein ligase as a novel candidate gene for altered quinine and quinidine responses in Plasmodium falciparumPlasmodium falciparum Na+/H+ Exchanger (pfnhe-1) Genetic Polymorphism in Indian Ocean Malaria-Endemic AreasA genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in KenyaMicrobial genomics and antimicrobial susceptibility testing.Polymorphisms in Pfmdr1, Pfcrt, and Pfnhe1 genes are associated with reduced in vitro activities of quinine in Plasmodium falciparum isolates from western KenyaIn vitro antimalarial susceptibility and molecular markers of drug resistance in Franceville, GabonLimited ability of Plasmodium falciparum pfcrt, pfmdr1, and pfnhe1 polymorphisms to predict quinine in vitro sensitivity or clinical effectiveness in UgandaPolymorphism of Plasmodium falciparum Na(+)/H(+) exchanger is indicative of a low in vitro quinine susceptibility in isolates from Viet Nam.The MSPDBL2 codon 591 polymorphism is associated with lumefantrine in vitro drug responses in Plasmodium falciparum isolates from Kilifi, KenyaMultidrug-resistant genotypes of Plasmodium falciparum, MyanmarPrevalence of Plasmodium falciparum anti-malarial resistance-associated polymorphisms in pfcrt, pfmdr1 and pfnhe1 in Muheza, Tanzania, prior to introduction of artemisinin combination therapy.Differential association of Plasmodium falciparum Na+/H+ exchanger polymorphism and quinine responses in field- and culture-adapted isolates of Plasmodium falciparum.Polymorphisms of the pfmdr1 but not the pfnhe-1 gene is associated with in vitro quinine sensitivity in Thai isolates of Plasmodium falciparumQuinine treatment selects the pfnhe-1 ms4760-1 polymorphism in Malian patients with Falciparum malariaIn vitro susceptibility to quinine and microsatellite variations of the Plasmodium falciparum Na+/H+ exchanger transporter (Pfnhe-1) gene in 393 isolates from Dakar, SenegalRepeat polymorphisms in the low-complexity regions of Plasmodium falciparum ABC transporters and associations with in vitro antimalarial responses.Antimalarial drugs: modes of action and mechanisms of parasite resistance.Drug-resistant malaria: molecular mechanisms and implications for public health.Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics.Baseline in vitro activities of the antimalarials pyronaridine and methylene blue against Plasmodium falciparum isolates from Kenya.Reduced in vitro doxycycline susceptibility in plasmodium falciparum field isolates from Kenya is associated with PfTetQ KYNNNN sequence polymorphism.Genetic linkage analyses redefine the roles of PfCRT and PfMDR1 in drug accumulation and susceptibility in Plasmodium falciparum.Amodiaquine resistance in Plasmodium berghei is associated with PbCRT His95Pro mutation, loss of chloroquine, artemisinin and primaquine sensitivity, and high transcript levels of key transporters.Screening of a library of traditional Chinese medicines to identify anti-malarial compounds and extracts.
P2860
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P2860
In vitro activities of quinine and other antimalarials and pfnhe polymorphisms in Plasmodium isolates from Kenya
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
In vitro activities of quinine ...... Plasmodium isolates from Kenya
@en
type
label
In vitro activities of quinine ...... Plasmodium isolates from Kenya
@en
prefLabel
In vitro activities of quinine ...... Plasmodium isolates from Kenya
@en
P2093
P2860
P356
P1476
In vitro activities of quinine ...... Plasmodium isolates from Kenya
@en
P2093
Alexis Nzila
Eric Ohuma
John Okombo
Josea Rono
Lynette Isabella Ochola
Steven M Kiara
P2860
P304
P356
10.1128/AAC.00325-10
P407
P577
2010-06-01T00:00:00Z