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Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

http://www.wikidata.org/entity/Q29615128

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Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparum Malaria in the Greater Mekong Subregion: heterogeneity and complexity Artemisinin-resistant malaria: research challenges, opportunities, and public health implications Declining artesunate-mefloquine efficacy against falciparum malaria on the Cambodia-Thailand border Pfmdr1 copy number and arteminisin derivatives combination therapy failure in falciparum malaria in Cambodia Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment Antimalarial drug resistance Artemisinin Resistance in Plasmodium falciparum Malaria A single amino acid residue can determine the sensitivity of SERCAs to artemisinins A molecular marker of artemisinin-resistant Plasmodium falciparum malaria Comparative whole genome transcriptome analysis of three Plasmodium falciparum strains.Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum Real-time quantitative PCR with SYBR Green I detection for estimating copy numbers of nine drug resistance candidate genes in Plasmodium falciparum Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure.The role of early detection and treatment in malaria elimination Antimalarial Drug Resistance: Literature Review and Activities and Findings of the ICEMR Network Plasmodium falciparum susceptibility to antimalarial drugs: global data issued from the Pasteur Institutes international network Global analysis of Plasmodium falciparum Na(+)/H(+) exchanger (pfnhe-1) allele polymorphism and its usefulness as a marker of in vitro resistance to quinine Malaria: progress, perils, and prospects for eradication Artemisinins: their growing importance in medicine Disruption of a Plasmodium falciparum Multidrug Resistance-associated Protein (PfMRP) Alters Its Fitness and Transport of Antimalarial Drugs and Glutathione Structural polymorphism in the promoter ofpfmrp2confersPlasmodium falciparumtolerance to quinoline drugs Genetic markers associated with dihydroartemisinin-piperaquine failure in Plasmodium falciparum malaria in Cambodia: a genotype-phenotype association study A HECT ubiquitin-protein ligase as a novel candidate gene for altered quinine and quinidine responses in Plasmodium falciparum PfCRT and its role in antimalarial drug resistance Evidence for a Central Role for PfCRT in Conferring Plasmodium falciparum Resistance to Diverse Antimalarial Agents Probing the multifactorial basis of Plasmodium falciparum quinine resistance: Evidence for a strain-specific contribution of the sodium-proton exchanger PfNHE Genome-wide association analysis identifies genetic loci associated with resistance to multiple antimalarials in Plasmodium falciparum from China-Myanmar border SnoopCGH: software for visualizing comparative genomic hybridization data Plasmodium falciparum: multifaceted resistance to artemisinins Characterization of drug resistance associated genetic polymorphisms among Plasmodium falciparum field isolates in Ujjain, Madhya Pradesh, India Artemisinin Action and Resistance in Plasmodium falciparum Advances in understanding the genetic basis of antimalarial drug resistance Genome-wide compensatory changes accompany drug- selected mutations in the Plasmodium falciparum crt gene Regulatory hotspots in the malaria parasite genome dictate transcriptional variation Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum Adaptive copy number evolution in malaria parasites A randomised controlled trial of artemether-lumefantrine versus artesunate for uncomplicated plasmodium falciparum treatment in pregnancy

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Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

http://www.wikidata.org/entity/Q29615128

description

article publié dans la revue scientifique The Lancet

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artikull shkencor

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artículu científicu

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scientific article published in The Lancet

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wetenschappelijk artikel

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գիտական հոդված

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գիտական յօդուած

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Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

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Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

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Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

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Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

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Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

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Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

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Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

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Alan Brockman

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Anne-Catrin Uhlemann

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Lucy Phaipun

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Nicholas J White

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Rina Patel

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Sornchai Looareesuwan

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P2860

Artemisinins target the SERCA of Plasmodium falciparum

Statistical methods for assessing agreement between two methods of clinical measurement

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum

Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance

A molecular marker for chloroquine-resistant falciparum malaria.

Selection for high-level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum.

Bioavailability and preliminary clinical efficacy of intrarectal artesunate in Ghanaian children with moderate malaria.

Plasmodium falciparum antimalarial drug susceptibility on the north-western border of Thailand during five years of extensive use of artesunate-mefloquine.

Measurement of trends in childhood malaria mortality in Africa: an assessment of progress toward targets based on verbal autopsy.

Antimalarial drug resistance and combination chemotherapy.

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438-447

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scholarly article

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17422

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10.1016/S0140-6736(04)16767-6

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9432

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364

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François H Nosten

Sanjeev Krishna

Elizabeth Dodds Ashley

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2004-07-01T00:00:00Z

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15288742

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Plasmodium falciparum

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