An atypical orthologue of 6-pyruvoyltetrahydropterin synthase can provide the missing link in the folate biosynthesis pathway of malaria parasites.
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Quantitative mass spectrometry catalogues Salmonella pathogenicity island-2 effectors and identifies their cognate host binding partnersTransition-state inhibitors of purine salvage and other prospective enzyme targets in malariaStructural basis of a novel activity of bacterial 6-pyruvoyltetrahydropterin synthase homologues distinct from mammalian 6-pyruvoyltetrahydropterin synthase activityAdaptive copy number evolution in malaria parasitesOrganic cofactors in the metabolism of Dehalococcoides mccartyi strainsA unique dual activity amino acid hydroxylase in Toxoplasma gondii.The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease.Functional promiscuity of the COG0720 familyThe Rickettsia Endosymbiont of Ixodes pacificus Contains All the Genes of De Novo Folate Biosynthesis.Comparative genomics guided discovery of two missing archaeal enzyme families involved in the biosynthesis of the pterin moiety of tetrahydromethanopterin and tetrahydrofolatePossible selection of host folate pathway gene polymorphisms in patients with malaria from a malaria endemic region in North East India.6-pyruvoyltetrahydropterin synthase paralogs replace the folate synthesis enzyme dihydroneopterin aldolase in diverse bacteria.Functional Annotations of Paralogs: A Blessing and a CurseExceptionally long-range haplotypes in Plasmodium falciparum chromosome 6 maintained in an endemic African population.Targeting the vitamin biosynthesis pathways for the treatment of malaria.Utility of the Biosynthetic Folate Pathway for Targets in Antimicrobial Discovery.Simple topological properties predict functional misannotations in a metabolic networkMRP1 mediates folate transport and antifolate sensitivity in Plasmodium falciparum.Use of thermal melt curves to assess the quality of enzyme preparationsA mathematical model of microbial folate biosynthesis and utilisation: implications for antifolate development.Wholly Rickettsia! Reconstructed Metabolic Profile of the Quintessential Bacterial Parasite of Eukaryotic Cells.Plasmodium falciparum: a paradigm for alternative folate biosynthesis in diverse microorganisms?
P2860
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P2860
An atypical orthologue of 6-pyruvoyltetrahydropterin synthase can provide the missing link in the folate biosynthesis pathway of malaria parasites.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
An atypical orthologue of 6-py ...... pathway of malaria parasites.
@en
type
label
An atypical orthologue of 6-py ...... pathway of malaria parasites.
@en
prefLabel
An atypical orthologue of 6-py ...... pathway of malaria parasites.
@en
P2093
P2860
P921
P1476
An atypical orthologue of 6-py ...... pathway of malaria parasites.
@en
P2093
Andrew M Blagborough
John E Hyde
Paul F G Sims
Sabine Dittrich
Sarah L Mitchell
P2860
P304
P356
10.1111/J.1365-2958.2007.06073.X
P407
P577
2007-12-18T00:00:00Z