Antimalarial activity of orotate analogs that inhibit dihydroorotase and dihydroorotate dehydrogenase.

Antimalarial activity of orotate analogs that inhibit dihydroorotase and dihydroorotate dehydrogenase.

Item
http://www.wikidata.org/entity/Q41940410
Structural determinants for the inhibitory ligands of orotidine-5′-monophosphate decarboxylaseEffects of atovaquone and other inhibitors on Pneumocystis carinii dihydroorotate dehydrogenaseTargeting purine and pyrimidine metabolism in human apicomplexan parasitesAntimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysisPlasmodium dihydroorotate dehydrogenase: a promising target for novel anti-malarial chemotherapy.Potent and selective activity of a combination of thymidine and 1843U89, a folate-based thymidylate synthase inhibitor, against Plasmodium falciparum.Leaving group activation and pyrophosphate ionic state at the catalytic site of Plasmodium falciparum orotate phosphoribosyltransferase.Malaria parasite carbonic anhydrase: inhibition of aromatic/heterocyclic sulfonamides and its therapeutic potential.Purine and pyrimidine pathways as targets in Plasmodium falciparum.Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy.Transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases.Transition state analogues of Plasmodium falciparum and human orotate phosphoribosyltransferases.Targeting the mitochondrial electron transport chain of Plasmodium falciparum: new strategies towards the development of improved antimalarials for the elimination era.Pyrophosphate interactions at the transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases
P2860

Antimalarial activity of orotate analogs that inhibit dihydroorotase and dihydroorotate dehydrogenase.

Item
http://www.wikidata.org/entity/Q41940410
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Antimalarial activity of orota ...... dihydroorotate dehydrogenase.
@en
type
label
Antimalarial activity of orota ...... dihydroorotate dehydrogenase.
@en
prefLabel
Antimalarial activity of orota ...... dihydroorotate dehydrogenase.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921
P356
P1433
P1476
Antimalarial activity of orota ...... dihydroorotate dehydrogenase.
@en
P2093
P304
P31
P356
10.1016/0006-2952(92)90506-E
P407
P433
P478
P577
P698
P921