Exogenous brain-derived neurotrophic factor rescues synaptic dysfunction in Mecp2-null mice
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Rett Syndrome: Crossing the Threshold to Clinical TranslationBDNF deregulation in Rett syndromeGABAergic signaling as therapeutic target for autism spectrum disordersGABA and glutamate pathways are spatially and developmentally affected in the brain of Mecp2-deficient miceAdvancing the understanding of autism disease mechanisms through geneticsA review of Rett syndrome (RTT) with induced pluripotent stem cellsThe Use of Induced Pluripotent Stem Cell Technology to Advance Autism Research and TreatmentRett syndrome: disruption of epigenetic control of postnatal neurological functionsModeling autistic features in animalsEx vivo treatment with a novel synthetic aminoglycoside NB54 in primary fibroblasts from Rett syndrome patients suppresses MECP2 nonsense mutationsTherapeutic Potential of Transcranial Focused Ultrasound for Rett Syndrome.A BDNF loop-domain mimetic acutely reverses spontaneous apneas and respiratory abnormalities during behavioral arousal in a mouse model of Rett syndrome.Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function.Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment.The cochlear CRF signaling systems and their mechanisms of action in modulating cochlear sensitivity and protection against trauma.Brain plasticity and disease: a matter of inhibition.Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome.Preclinical research in Rett syndrome: setting the foundation for translational success.Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons.Effect of Sarizotan, a 5-HT1a and D2-like receptor agonist, on respiration in three mouse models of Rett syndromeNeuroanatomy in mouse models of Rett syndrome is related to the severity of Mecp2 mutation and behavioral phenotypes.Respiratory phenotypes are distinctly affected in mice with common Rett syndrome mutations MeCP2 T158A and R168X.Neuronal activity-regulated gene transcription in synapse development and cognitive function.Chronic intermittent hypoxia affects integration of sensory input by neurons in the nucleus tractus solitariiCell-autonomous alterations in dendritic arbor morphology and connectivity induced by overexpression of MeCP2 in Xenopus central neurons in vivo7,8-dihydroxyflavone exhibits therapeutic efficacy in a mouse model of Rett syndromeExperimental models of Rett syndrome based on Mecp2 dysfunction.MeCP2 regulates the synaptic expression of a Dysbindin-BLOC-1 network component in mouse brain and human induced pluripotent stem cell-derived neurons.Abnormal expression of cerebrospinal fluid cation chloride cotransporters in patients with Rett syndromeExcitation/inhibition imbalance and impaired synaptic inhibition in hippocampal area CA3 of Mecp2 knockout miceComplexities of Rett syndrome and MeCP2Network models predict that reduced excitatory fluctuations can give rise to hippocampal network hyper-excitability in MeCP2-null miceBrain-derived neurotrophic factor inhibits calcium channel activation, exocytosis, and endocytosis at a central nerve terminal.The disruption of central CO2 chemosensitivity in a mouse model of Rett syndrome.Synaptic microcircuit dysfunction in genetic models of neurodevelopmental disorders: focus on Mecp2 and Met.Synaptic dysfunction in neurodevelopmental disorders associated with autism and intellectual disabilities.Glia determine the course of brain-derived neurotrophic factor-mediated dendritogenesis and provide a soluble inhibitory cue to dendritic growth in the brainstemRett syndrome: genes, synapses, circuits, and therapeuticsEffect of hyperoxic exposure during early development on neurotrophin expression in the carotid body and nucleus tractus solitarii.Cellular mechanisms of activity-dependent BDNF expression in primary sensory neurons.
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P2860
Exogenous brain-derived neurotrophic factor rescues synaptic dysfunction in Mecp2-null mice
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Exogenous brain-derived neurot ...... dysfunction in Mecp2-null mice
@en
type
label
Exogenous brain-derived neurot ...... dysfunction in Mecp2-null mice
@en
prefLabel
Exogenous brain-derived neurot ...... dysfunction in Mecp2-null mice
@en
P2093
P2860
P1476
Exogenous brain-derived neurot ...... dysfunction in Mecp2-null mice
@en
P2093
David M Katz
Diana L Kunze
Michael Ogier
P2860
P304
P356
10.1523/JNEUROSCI.5503-09.2010
P407
P577
2010-04-01T00:00:00Z