Validation of the multiple sensor mechanism of the Keap1-Nrf2 system
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Redox signaling regulated by electrophiles and reactive sulfur speciesThe Nrf2/HO-1 Axis in Cancer Cell Growth and ChemoresistancePharmacology and Clinical Drug Candidates in Redox MedicineRoles nrf2 plays in myeloid cells and related disordersStructure of the BTB domain of Keap1 and its interaction with the triterpenoid antagonist CDDONrf2 mediates redox adaptations to exerciseNrf2 Is an Attractive Therapeutic Target for Retinal DiseasesMechanisms of Nrf2/Keap1-dependent phase II cytoprotective and detoxifying gene expression and potential cellular targets of chemopreventive isothiocyanatesSchisandra chinensis regulates drug metabolizing enzymes and drug transporters via activation of Nrf2-mediated signaling pathwayA generalizable platform for interrogating target- and signal-specific consequences of electrophilic modifications in redox-dependent cell signalingThe complexity of the Nrf2 pathway: beyond the antioxidant responseMechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseaseThe clinical potential of influencing Nrf2 signaling in degenerative and immunological disordersNrf2 and Nrf2-related proteins in development and developmental toxicity: Insights from studies in zebrafish (Danio rerio)Nrf2-Mediated Regulation of Skeletal Muscle Glycogen MetabolismFrequency Modulated Translocational Oscillations of Nrf2 Mediate the Antioxidant Response Element Cytoprotective Transcriptional Response.Role of Nuclear Factor Erythroid 2-Related Factor 2 in Diabetic Nephropathy.Evidence for a novel antioxidant function and isoform-specific regulation of the human p66Shc gene.Visualization of the Drosophila dKeap1-CncC interaction on chromatin illumines cooperative, xenobiotic-specific gene activation.Frugal chemoprevention: targeting Nrf2 with foods rich in sulforaphaneTopical application of RTA 408 lotion activates Nrf2 in human skin and is well-tolerated by healthy human volunteersToll-Like Receptor Signaling Induces Nrf2 Pathway Activation through p62-Triggered Keap1 Degradation.Protective Effects of L-Malate against Myocardial Ischemia/Reperfusion Injury in RatsNrf2--a therapeutic target for the treatment of neurodegenerative diseases.Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation.Cell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell diseaseRegulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complexThe Role of Sulfhydryl Reactivity of Small Molecules for the Activation of the KEAP1/NRF2 Pathway and the Heat Shock ResponseAntioxidant capacity of phytochemicals and their potential effects on oxidative status in animals - A review.Modification of cysteine residues by cyclopentenone prostaglandins: interplay with redox regulation of protein function.Pathophysiology of tobacco smoke exposure: recent insights from comparative and redox proteomics.Role of the Nrf2 signaling system in health and disease.Conservation of the Keap1-Nrf2 System: An Evolutionary Journey through Stressful Space and Time.Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells.Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate.TAK1 Regulates the Nrf2 Antioxidant System Through Modulating p62/SQSTM1.Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response.HX-1171, a Novel Nrf2 Activator, Induces NQO1 and HMOX1 Expression.Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants.Fibroblast growth factor 21 and its novel association with oxidative stress.
P2860
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P2860
Validation of the multiple sensor mechanism of the Keap1-Nrf2 system
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Validation of the multiple sensor mechanism of the Keap1-Nrf2 system
@en
type
label
Validation of the multiple sensor mechanism of the Keap1-Nrf2 system
@en
prefLabel
Validation of the multiple sensor mechanism of the Keap1-Nrf2 system
@en
P2093
P2860
P1476
Validation of the multiple sensor mechanism of the Keap1-Nrf2 system
@en
P2093
Hozumi Motohashi
Kai Takaya
Ko Onodera
Masayuki Yamamoto
Susumu Satomi
Takafumi Suzuki
Thomas W Kensler
P2860
P304
P356
10.1016/J.FREERADBIOMED.2012.06.023
P577
2012-06-23T00:00:00Z