Repression of chondrogenesis through binding of notch signaling proteins HES-1 and HEY-1 to N-box domains in the COL2A1 enhancer site.
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REX-1 expression and p38 MAPK activation status can determine proliferation/differentiation fates in human mesenchymal stem cellsPotential mechanisms underlying the Runx2 induced osteogenesis of bone marrow mesenchymal stem cellsGenes that regulate morphogenesis and growth of the temporomandibular joint: a reviewTargeted In Situ Biosynthetic Transcriptional Activation in Native Surface-Level Human Articular Chondrocytes during Lesion StabilizationMesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritisMicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responsesNotch and the skeleton.RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance.Sox9 transcriptionally represses Spp1 to prevent matrix mineralization in maturing heart valves and chondrocytesTranscriptional enhancers in protein-coding exons of vertebrate developmental genes.HES1 (hairy and enhancer of split 1) is a determinant of bone massMesenchymal chondroprogenitor cell origin and therapeutic potentialRepression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.The versatile functions of Sox9 in development, stem cells, and human diseasesThe role of the Notch pathway in healthy and osteoarthritic articular cartilage: from experimental models to ex vivo studies.Expression patterns and function of chromatin protein HMGB2 during mesenchymal stem cell differentiation.Notch signaling represses GATA4-induced expression of genes involved in steroid biosynthesisMultifaceted signaling regulators of chondrogenesis: Implications in cartilage regeneration and tissue engineeringNotch suppresses nuclear factor of activated T cells (NFAT) transactivation and Nfatc1 expression in chondrocytesSelection of cell fate in the organ of Corti involves the integration of Hes/Hey signaling at the Atoh1 promoter.Notch Signaling and the Skeleton.HES factors regulate specific aspects of chondrogenesis and chondrocyte hypertrophy during cartilage developmentInterleukin 6 mediates selected effects of Notch in chondrocytes.Icariin improves osteoporosis, inhibits the expression of PPARγ, C/EBPα, FABP4 mRNA, N1ICD and jagged1 proteins, and increases Notch2 mRNA in ovariectomized rats.Reconstruction of an in vitro niche for the transition from intervertebral disc development to nucleus pulposus regeneration.The NOTCH Ligand JAG1 Regulates GDNF Expression in Sertoli Cells.Notch signaling components are upregulated during both endochondral and intramembranous bone regeneration.Hypoxia activates the notch signaling pathway in cells of the intervertebral disc: implications in degenerative disc disease.Notch1 signaling regulates chondrogenic lineage determination through Sox9 activation.Inhibition of Notch1 promotes hedgehog signalling in a HES1-dependent manner in chondrocytes and exacerbates experimental osteoarthritis.The Oncogene LRF Stimulates Proliferation of Mesenchymal Stem Cells and Inhibits Their Chondrogenic Differentiation.Comparative analysis with collagen type II distinguishes cartilage oligomeric matrix protein as a primary TGFβ-responsive gene.Set7/9 impacts COL2A1 expression through binding and repression of SirT1 histone deacetylation.Recapitulation of mesenchymal condensation enhances in vitro chondrogenesis of human mesenchymal stem cells.Autocrine Action of Thrombospondin-2 Determines the Chondrogenic Differentiation Potential and Suppresses Hypertrophic Maturation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells.
P2860
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P2860
Repression of chondrogenesis through binding of notch signaling proteins HES-1 and HEY-1 to N-box domains in the COL2A1 enhancer site.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Repression of chondrogenesis t ...... s in the COL2A1 enhancer site.
@en
type
label
Repression of chondrogenesis t ...... s in the COL2A1 enhancer site.
@en
prefLabel
Repression of chondrogenesis t ...... s in the COL2A1 enhancer site.
@en
P2093
P2860
P356
P1476
Repression of chondrogenesis t ...... s in the COL2A1 enhancer site.
@en
P2093
Koji Hiraoka
Martin K Lotz
Shawn P Grogan
Tsaiwei Olee
P2860
P304
P356
10.1002/ART.23730
P577
2008-09-01T00:00:00Z