cAMP-activated Ca2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways.
about
Pharmacological implications of the Ca(2+)/cAMP signaling interaction: from risk for antihypertensive therapy to potential beneficial for neurological and psychiatric disordersAirway Gland Structure and FunctionInvestigating CFTR and KCa3.1 Protein/Protein InteractionsAssessing mucociliary transport of single particles in vivo shows variable speed and preference for the ventral trachea in newborn pigsMarked increases in mucociliary clearance produced by synergistic secretory agonists or inhibition of the epithelial sodium channel.Mechanism and synergism in epithelial fluid and electrolyte secretion.cAMP and Ca²⁺ signaling in secretory epithelia: crosstalk and synergism.Gel-forming mucins form distinct morphologic structures in airwaysDefective fluid secretion from submucosal glands of nasal turbinates from CFTR-/- and CFTR (ΔF508/ΔF508) pigs.Physiology of epithelial chloride and fluid secretionMolecular mechanisms of calcium-sensing receptor-mediated calcium signaling in the modulation of epithelial ion transport and bicarbonate secretionThe absence of mrp4 has no effect on the recruitment of neutrophils and eosinophils into the lung after LPS, cigarette smoke or allergen challenge.Intracellular Cl- as a signaling ion that potently regulates Na+/HCO3- transporters.In vivo readout of CFTR function: ratiometric measurement of CFTR-dependent secretion by individual, identifiable human sweat glandsCGRP induction in cystic fibrosis airways alters the submucosal gland progenitor cell niche in mice.Mucous solids and liquid secretion by airways: studies with normal pig, cystic fibrosis human, and non-cystic fibrosis human bronchi.Cystic fibrosis and the relationship between mucin and chloride secretion by cultures of human airway gland mucous cells.Mucociliary transport in porcine trachea: differential effects of inhibiting chloride and bicarbonate secretion.New animal models of cystic fibrosis: what are they teaching us?Effect of VIP on intracellular [Ca2+], extracellular regulated kinase 1/2, and secretion in cultured rat conjunctival goblet cells.Bitter and sweet taste receptors in the respiratory epithelium in health and diseaseTaste receptors in innate immunityHypercapnia modulates cAMP signalling and cystic fibrosis transmembrane conductance regulator-dependent anion and fluid secretion in airway epithelia.Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor.A novel fluorescent sensor for measurement of CFTR function by flow cytometry.Novel role for pendrin in orchestrating bicarbonate secretion in cystic fibrosis transmembrane conductance regulator (CFTR)-expressing airway serous cells.Acute intratracheal Pseudomonas aeruginosa infection in cystic fibrosis mice is age-independent.Taste Receptors: Regulators of Sinonasal Innate Immunity.CK2 is a key regulator of SLC4A2-mediated Cl-/HCO3- exchange in human airway epithelia.Why mouse airway submucosal gland serous cells do not secrete fluid in response to cAMP stimulation.Transgenic animals may help resolve a sticky situation in cystic fibrosis.Epithelial Chloride Transport by CFTR Requires TMEM16A.Simulation of Cl(-) Secretion in Epithelial Tissues: New Methodology Estimating Activity of Electro-Neutral Cl(-) Transporter.Protease-activated receptor 2 activates airway apical membrane chloride permeability and increases ciliary beating.Impaired PGE2-stimulated Cl- and HCO3- secretion contributes to cystic fibrosis airway disease.Activation of airway epithelial bitter taste receptors by Pseudomonas aeruginosa quinolones modulates calcium, cyclic-AMP, and nitric oxide signaling.
P2860
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P2860
cAMP-activated Ca2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
cAMP-activated Ca2+ signaling ...... in porcine and human airways.
@en
cAMP-activated Ca2+ signaling ...... in porcine and human airways.
@nl
type
label
cAMP-activated Ca2+ signaling ...... in porcine and human airways.
@en
cAMP-activated Ca2+ signaling ...... in porcine and human airways.
@nl
prefLabel
cAMP-activated Ca2+ signaling ...... in porcine and human airways.
@en
cAMP-activated Ca2+ signaling ...... in porcine and human airways.
@nl
P2860
P356
P1476
cAMP-activated Ca2+ signaling ...... n in porcine and human airways
@en
P2093
J Kevin Foskett
P2860
P304
P356
10.1172/JCI42992
P407
P50
P577
2010-08-25T00:00:00Z