Modulation of protein aggregation by polyethylene glycol conjugation: GCSF as a case study.
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Macromolecule-assisted de novo protein foldingToward top-down determination of PEGylation site using MALDI in-source decay MS analysis.Design, synthesis, characterization and in-vivo activity of a novel salmon calcitonin conjugate containing a novel PEG-lipid moiety.Conformational and aggregation properties of a PEGylated alanine-rich polypeptidePEGylation of concanavalin A to improve its stability for an in vivo glucose sensing assayBiophysical characterization of Met-G-CSF: effects of different site-specific mono-pegylations on protein stability and aggregation.Chaperoning roles of macromolecules interacting with proteins in vivo.Prevention of benzyl alcohol-induced aggregation of chymotrypsinogen by PEGylation.Preferential Interactions and the Effect of Protein PEGylation.Fully Synthetic Granulocyte Colony-Stimulating Factor Enabled by Isonitrile-Mediated Coupling of Large, Side-Chain-Unprotected PeptidesPEGylated interferon beta-1a in the treatment of multiple sclerosis - an update.Effects of glycosylation on the stability of protein pharmaceuticals.Single-Step Purification of Ovalbumin from Egg White Using Aqueous Biphasic Systems.An anti-TNF-α antibody mimetic to treat ocular inflammation.Delivery of therapeutic proteins.Basics and recent advances in peptide and protein drug delivery.PEGylation and its impact on the design of new protein-based medicines.Characterizing the Structure and Oligomerization of Major Royal Jelly Protein 1 (MRJP1) by Mass Spectrometry and Complementary Biophysical Tools.A sensitive WST-8-based bioassay for PEGylated granulocyte colony stimulating factor using the NFS-60 cell line.Nonspecific shielding of unfavorable electrostatic intramolecular interactions in the erythropoietin native-state increase conformational stability and limit non-native aggregation.Using hydrogen/deuterium exchange mass spectrometry to study conformational changes in granulocyte colony stimulating factor upon PEGylation.Therapeutic anti-IgE monoclonal antibody single chain variable fragment (scFv) safety and immunomodulatory effects after one time injection in four dogs.Characterization of disulfide linkages in recombinant human granulocyte-colony stimulating factor.Microfiltration of enzyme treated egg whites for accelerated detection of viable Salmonella.Disulfide-bridging PEGylation during refolding for the more efficient production of modified proteins.
P2860
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P2860
Modulation of protein aggregation by polyethylene glycol conjugation: GCSF as a case study.
description
2006 nî lūn-bûn
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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2006年论文
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2006年论文
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name
Modulation of protein aggregat ...... ugation: GCSF as a case study.
@en
Modulation of protein aggregat ...... ugation: GCSF as a case study.
@nl
type
label
Modulation of protein aggregat ...... ugation: GCSF as a case study.
@en
Modulation of protein aggregat ...... ugation: GCSF as a case study.
@nl
prefLabel
Modulation of protein aggregat ...... ugation: GCSF as a case study.
@en
Modulation of protein aggregat ...... ugation: GCSF as a case study.
@nl
P2093
P2860
P356
P1433
P1476
Modulation of protein aggregat ...... ugation: GCSF as a case study.
@en
P2093
Alexis M K Lueras
Christopher Sloey
David N Brems
Heather Yeghnazar
Hiromi Arai
Michael Treuheit
Mohini Aras
Olaf Kinstler
Rahul S Rajan
Robert Briddell
P2860
P304
P356
10.1110/PS.052004006
P577
2006-04-05T00:00:00Z