Versican proteolysis mediates myocardial regression during outflow tract development.
about
Versican and the regulation of cell phenotype in diseaseWhole-exome sequencing reveals TopBP1 as a novel gene in idiopathic pulmonary arterial hypertensionLumican deficiency results in cardiomyocyte hypertrophy with altered collagen assemblyEndothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndromeEndocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesisThe multiple, complex roles of versican and its proteolytic turnover by ADAMTS proteases during embryogenesis.Isolation and purification of versican and analysis of versican proteolysis.Serotonin potentiates transforming growth factor-beta3 induced biomechanical remodeling in avian embryonic atrioventricular valves.Chromatin remodeling in cardiovascular development and physiology.BMP-2 induces versican and hyaluronan that contribute to post-EMT AV cushion cell migration.A link between smooth muscle cell death and extracellular matrix degradation during vascular atrophyImbalanced expression of Vcan mRNA splice form proteins alters heart morphology and cellular protein profiles.Extracellular processing of the cartilage proteoglycan aggregate and its effect on CD44-mediated internalization of hyaluronanProteolytic cleavage of versican and involvement of ADAMTS-1 in VEGF-A/VPF-induced pathological angiogenesis.Small leucine-rich proteoglycans exhibit unique spatiotemporal expression profiles during cardiac valve development.Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.Insufficient versican cleavage and Smad2 phosphorylation results in bicuspid aortic and pulmonary valvesThe ADAMTS1 protease gene is required for mammary tumor growth and metastasis.Caveolin-1 deletion exacerbates cardiac interstitial fibrosis by promoting M2 macrophage activation in mice after myocardial infarction.Expression of V3 Versican by Rat Arterial Smooth Muscle Cells Promotes Differentiated and Anti-inflammatory PhenotypesFibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferationTranscriptional Impact of Rare and Private Copy Number Variants in Hypoplastic Left Heart SyndromeCartilage link protein 1 (Crtl1), an extracellular matrix component playing an important role in heart development.Correlation of Versican Expression, Accumulation, and Degradation during Embryonic Development by Quantitative ImmunohistochemistryAdamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues.ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression.Extracellular matrix and heart development.Molecular regulation of cardiomyocyte differentiation.Provisional matrix: A role for versican and hyaluronan.Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies.Development of myotendinous-like junctions that anchor cardiac valves requires fibromodulin and lumican.Versican G1 domain and V3 isoform overexpression results in increased chondrogenesis in the developing chick limb in ovo.The role of versican isoforms V0/V1 in glioma migration mediated by transforming growth factor-beta2.Proteolytic cleavage of versican during limb joint development.Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation.Versican knockdown reduces interzone area during early stages of chick synovial joint development.Differentiation of cardiomyocytes from human embryonic stem cells is accompanied by changes in the extracellular matrix production of versican and hyaluronan.ADAMTS1 cleavage of versican mediates essential structural remodeling of the ovarian follicle and cumulus-oocyte matrix during ovulation in mice.Versican: a novel modulator of hepatic fibrosis.Anatomical correlates relevant to ablation above the semilunar valves for the cardiac electrophysiologist: a study of 603 hearts
P2860
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P2860
Versican proteolysis mediates myocardial regression during outflow tract development.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Versican proteolysis mediates myocardial regression during outflow tract development.
@en
Versican proteolysis mediates myocardial regression during outflow tract development.
@nl
type
label
Versican proteolysis mediates myocardial regression during outflow tract development.
@en
Versican proteolysis mediates myocardial regression during outflow tract development.
@nl
prefLabel
Versican proteolysis mediates myocardial regression during outflow tract development.
@en
Versican proteolysis mediates myocardial regression during outflow tract development.
@nl
P2093
P2860
P356
P1476
Versican proteolysis mediates myocardial regression during outflow tract development.
@en
P2093
Christine B Kern
Corey H Mjaatvedt
Leticia Reyes
Robert P Thompson
Roger R Markwald
Russell A Norris
Sarah E Fairey
Stanley Hoffman
W Scott Argraves
P2860
P304
P356
10.1002/DVDY.21059
P577
2007-03-01T00:00:00Z