Inhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis.
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Notch inhibits apoptosis by direct interference with XIAP ubiquitination and degradationA small molecule inhibitor of XIAP induces apoptosis and synergises with vinorelbine and cisplatin in NSCLC.Transient pockets on XIAP-BIR2: toward the characterization of putative binding sites of small-molecule XIAP inhibitors.CD74 interferes with the expression of fas receptor on the surface of lymphoma cellsThe Fas/CD95 Receptor Regulates the Death of Autoreactive B Cells and the Selection of Antigen-Specific B Cells.Small-molecule XIAP antagonist restores caspase-9 mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cellsTNFR-associated factor 2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice.Inhibitor of apoptosis proteins in hematological malignancies.Overexpression of the Fas-inhibitory molecule TOSO: a novel antiapoptotic factor in chronic lymphocytic leukemia.Exploiting inhibitor of apoptosis proteins as therapeutic targets in hematological malignancies.AdCD40L--crossing the valley of death?Inhibitor of Apoptosis (IAP) proteins in hematological malignancies: molecular mechanisms and therapeutic opportunities.MiR-138: A promising therapeutic target for cancer.Double inhibition of XIAP and Bcl-2 axis is beneficial for retrieving sensitivity of renal cell cancer to apoptosis.Targeting the apoptotic machinery in pancreatic cancers using small-molecule antagonists of the X-linked inhibitor of apoptosis protein.CD154 induces p73 to overcome the resistance to apoptosis of chronic lymphocytic leukemia cells lacking functional p53.CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex.Selective IAP inhibition results in sensitization of unstimulated but not CD40-stimulated chronic lymphocytic leukaemia cells to TRAIL-induced apoptosis.miRs-138 and -424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in CLL.Downregulation of miR-374b-5p promotes chemotherapeutic resistance in pancreatic cancer by upregulating multiple anti-apoptotic proteins.
P2860
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P2860
Inhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Inhibitors of XIAP sensitize C ...... ls to CD95-mediated apoptosis.
@en
Inhibitors of XIAP sensitize C ...... ls to CD95-mediated apoptosis.
@nl
type
label
Inhibitors of XIAP sensitize C ...... ls to CD95-mediated apoptosis.
@en
Inhibitors of XIAP sensitize C ...... ls to CD95-mediated apoptosis.
@nl
prefLabel
Inhibitors of XIAP sensitize C ...... ls to CD95-mediated apoptosis.
@en
Inhibitors of XIAP sensitize C ...... ls to CD95-mediated apoptosis.
@nl
P2093
P2860
P1433
P1476
Inhibitors of XIAP sensitize C ...... ls to CD95-mediated apoptosis.
@en
P2093
Adel Nefzi
Arnon P Kater
Clemencia Pinilla
Frank Dicker
John C Reed
John Ostresh
Kate Welsh
Massimo Mangiola
Richard Houghten
Thomas J Kipps
P2860
P304
P356
10.1182/BLOOD-2005-02-0695
P407
P577
2005-05-24T00:00:00Z