Epitope-tagged receptor knock-in mice reveal that differential desensitization of alpha2-adrenergic responses is because of ligand-selective internalization
about
Desensitized D2 autoreceptors are resistant to trafficking.α(2A)-adrenergic receptors filter parabrachial inputs to the bed nucleus of the stria terminalisEnhanced hypotensive, bradycardic, and hypnotic responses to alpha2-adrenergic agonists in spinophilin-null mice are accompanied by increased G protein coupling to the alpha2A-adrenergic receptorCannabinoid modulation of alpha2 adrenergic receptor function in rodent medial prefrontal cortexA single lys residue on the first intracellular loop modulates the endoplasmic reticulum export and cell-surface expression of α2A-adrenergic receptorThe antidepressant desipramine is an arrestin-biased ligand at the α(2A)-adrenergic receptor driving receptor down-regulation in vitro and in vivo.Therapeutic potential of β-arrestin- and G protein-biased agonists.Cross-talk from β-adrenergic receptors modulates α2A-adrenergic receptor endocytosis in sympathetic neurons via protein kinase A and spinophilin.alpha2A-adrenergic receptors heterosynaptically regulate glutamatergic transmission in the bed nucleus of the stria terminalis.Are the pharmacology and physiology of α₂ adrenoceptors determined by α₂-heteroreceptors and autoreceptors respectively?Cortical adrenoceptor expression, function and adaptation under conditions of cannabinoid receptor deletion.Strategy for Identification of Phosphorylation Levels of Low Abundance Proteins in Vivo for Which Antibodies Are not Available.The amyloid precursor protein modulates α2A-adrenergic receptor endocytosis and signaling through disrupting arrestin 3 recruitment.Diverse arrestin-recruiting and endocytic profiles of tricyclic antipsychotics acting as direct α2A adrenergic receptor ligands.
P2860
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P2860
Epitope-tagged receptor knock-in mice reveal that differential desensitization of alpha2-adrenergic responses is because of ligand-selective internalization
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Epitope-tagged receptor knock- ...... gand-selective internalization
@en
Epitope-tagged receptor knock- ...... gand-selective internalization
@nl
type
label
Epitope-tagged receptor knock- ...... gand-selective internalization
@en
Epitope-tagged receptor knock- ...... gand-selective internalization
@nl
prefLabel
Epitope-tagged receptor knock- ...... gand-selective internalization
@en
Epitope-tagged receptor knock- ...... gand-selective internalization
@nl
P2093
P2860
P356
P1476
Epitope-tagged receptor knock- ...... gand-selective internalization
@en
P2093
Angela D Shields
Danny G Winder
Lee E Limbird
Roujian Lu
Timothy Angelotti
Youwen Zhang
Yunjia Chen
P2860
P304
13233-13243
P356
10.1074/JBC.M807535200
P407
P50
P577
2009-03-10T00:00:00Z