S1P1 receptor localization confers selectivity for Gi-mediated cAMP and contractile responses
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The role of sphingosine-1-phosphate in endothelial barrier functionSphingosine kinase and sphingosine 1-phosphate in the heart: a decade of progressThe clinically-tested S1P receptor agonists, FTY720 and BAF312, demonstrate subtype-specific bradycardia (S1P₁) and hypertension (S1P₃) in ratAn entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondriaFocal adhesion kinase as a RhoA-activable signaling scaffold mediating Akt activation and cardiomyocyte protectionPAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiologySphingosine kinase and sphingosine 1-phosphate in cardioprotection.Cardiomyocyte S1P1 receptor-mediated extracellular signal-related kinase signaling and desensitizationHigh-density lipoprotein determines adult mouse cardiomyocyte fate after hypoxia-reoxygenation through lipoprotein-associated sphingosine 1-phosphate.Targeting of tumor necrosis factor receptor 1 to low density plasma membrane domains in human endothelial cells.Predictability of peripheral lymphocyte reduction of novel S1P1 agonists by in vitro GPCR signaling profile.Hematopoietic sphingosine 1-phosphate lyase deficiency decreases atherosclerotic lesion development in LDL-receptor deficient miceRegulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.APJ acts as a dual receptor in cardiac hypertrophy.Mannose-capped lipoarabinomannan from Mycobacterium tuberculosis preferentially inhibits sphingosine-1-phosphate-induced migration of Th1 cells.Sphingolipids in cardiovascular and cerebrovascular systems: Pathological implications and potential therapeutic targets.Implication of sphingosin-1-phosphate in cardiovascular regulation.Sphingolipid signaling and treatment during remodeling of the uninfarcted ventricular wall after myocardial infarction.Membrane rafts and caveolae in cardiovascular signalingSphingosine-1-phosphate receptor signalling in the heart.G protein-dependent and G protein-independent signaling pathways and their impact on cardiac function.Lysophospholipid receptor activation of RhoA and lipid signaling pathways.β1-adrenergic receptor and sphingosine-1-phosphate receptor 1 (S1PR1) reciprocal downregulation influences cardiac hypertrophic response and progression to heart failure: protective role of S1PR1 cardiac gene therapyBiological Effects of Naturally Occurring Sphingolipids, Uncommon Variants, and Their Analogs.Sphingosine-1-phosphate inhibits differentiation of C3H10T1/2 cells into adipocyte.Sphingosine-1-phosphate rapidly increases cortisol biosynthesis and the expression of genes involved in cholesterol uptake and transport in H295R adrenocortical cellsSphingosine 1-phosphate elicits RhoA-dependent proliferation and MRTF-A mediated gene induction in CPCs.Sphingosine Kinases and Sphingosine 1-Phosphate Receptors: Signaling and Actions in the Cardiovascular System.PHLPP-1 negatively regulates Akt activity and survival in the heart.Involvement of S1P1 receptor pathway in angiogenic effects of a novel adenosine-like nucleic acid analog COA-Cl in cultured human vascular endothelial cells.Protease-activated receptor 1 (PAR1) coupling to G(q/11) but not to G(i/o) or G(12/13) is mediated by discrete amino acids within the receptor second intracellular loop.Bioluminescence imaging of G protein-coupled receptor activation in living mice.Sphingosine-1-Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning.G protein coupled receptor signaling complexes in live cells.Selective coupling of the S1P3 receptor subtype to S1P-mediated RhoA activation and cardioprotection.Sphingosine-1-Phosphate Promotes the Persistence of Activated CD4 T Cells in Inflamed Sites.
P2860
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P2860
S1P1 receptor localization confers selectivity for Gi-mediated cAMP and contractile responses
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
S1P1 receptor localization con ...... cAMP and contractile responses
@en
S1P1 receptor localization con ...... cAMP and contractile responses
@nl
type
label
S1P1 receptor localization con ...... cAMP and contractile responses
@en
S1P1 receptor localization con ...... cAMP and contractile responses
@nl
prefLabel
S1P1 receptor localization con ...... cAMP and contractile responses
@en
S1P1 receptor localization con ...... cAMP and contractile responses
@nl
P2093
P2860
P356
P1476
S1P1 receptor localization con ...... cAMP and contractile responses
@en
P2093
Christopher Kable Means
Jerold Chun
Joan Heller Brown
Shigeki Miyamoto
P2860
P304
11954-11963
P356
10.1074/JBC.M707422200
P407
P577
2008-02-24T00:00:00Z