Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma
about
Molecular Details of Olfactomedin Domains Provide Pathway to Structure-Function StudiesStructure-activity relationship in a purine-scaffold compound series with selectivity for the endoplasmic reticulum Hsp90 paralog Grp94Higher incidence of steroid-induced ocular hypertension in keratoconusChemical Tools to Investigate Mechanisms Associated with HSP90 and HSP70 in Disease.Development of Glucose Regulated Protein 94-Selective Inhibitors Based on the BnIm and Radamide ScaffoldNatural Product Inspired N-Terminal Hsp90 Inhibitors: From Bench to Bedside?Targeting the ER-autophagy system in the trabecular meshwork to treat glaucomaDiscovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions.Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma.Resorcinol-Based Grp94-Selective Inhibitors.Second Generation Grp94-Selective Inhibitors Provide Opportunities for the Inhibition of Metastatic Cancer.Transformation of the Non-Selective Aminocyclohexanol-Based Hsp90 Inhibitor into a Grp94-Seletive Scaffold.Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding.
P2860
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P2860
Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma
@en
Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma
@nl
type
label
Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma
@en
Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma
@nl
prefLabel
Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma
@en
Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma
@nl
P2093
P2860
P356
P1476
Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma
@en
P2093
Amirthaa Suntharalingam
Andrew R Stothert
Brian S J Blagg
Chad A Dickey
Dustin J E Huard
Raquel L Lieberman
Sanket Mishra
Sarah N Fontaine
P2860
P304
P356
10.1093/HMG/DDU367
P577
2014-07-15T00:00:00Z