20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells.
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Vascular actions of 20-HETE20-HETE and blood pressure regulation: clinical implicationsEffect of 20-HETE inhibition on infarct volume and cerebral blood flow after transient middle cerebral artery occlusion.Regulation of NADPH oxidase in vascular endothelium: the role of phospholipases, protein kinases, and cytoskeletal proteins.Vascular characterization of mice with endothelial expression of cytochrome P450 4F2.20-HETE-induced nitric oxide production in pulmonary artery endothelial cells is mediated by NADPH oxidase, H2O2, and PI3-kinase/Akt.Hypoxia preconditioning increases survival and decreases expression of Toll-like receptor 4 in pulmonary artery endothelial cells exposed to lipopolysaccharide.The role of 20-HETE in androgen-mediated hypertension.20-HETE increases NADPH oxidase-derived ROS production and stimulates the L-type Ca2+ channel via a PKC-dependent mechanism in cardiomyocytes2,3',4,5'-Tetramethoxystilbene prevents deoxycorticosterone-salt-induced hypertension: contribution of cytochrome P-450 1B120-Hydroxyeicosatetraenoic acid impairs endothelial insulin signaling by inducing phosphorylation of the insulin receptor substrate-1 at Ser616.Cytochrome P450 1B1 contributes to renal dysfunction and damage caused by angiotensin II in mice.Involvement of cytochrome P-450 1B1 in renal dysfunction, injury, and inflammation associated with angiotensin II-induced hypertension in rats.Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures.Contribution of cytochrome P450 1B1 to hypertension and associated pathophysiology: a novel target for antihypertensive agents.Activation of JNK/c-Jun is required for the proliferation, survival, and angiogenesis induced by EET in pulmonary artery endothelial cells.Treatment with the cytochrome P450 ω-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats.20-HETE-induced mitochondrial superoxide production and inflammatory phenotype in vascular smooth muscle is prevented by glucose-6-phosphate dehydrogenase inhibition.Expression of CYP4A1 in U251 human glioma cell induces hyperproliferative phenotype in vitro and rapidly growing tumors in vivo.Tissue protection and endothelial cell signaling by 20-HETE analogs in intact ex vivo lung slices.20-HETE increases survival and decreases apoptosis in pulmonary arteries and pulmonary artery endothelial cells20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertensionClinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic TargetReactive oxygen species as therapeutic targets in pulmonary hypertension.The cardioprotection of dihydrotanshinone I against myocardial ischemia-reperfusion injury via inhibition of arachidonic acid ω-hydroxylase.Nrf2 Activation by 5-lipoxygenase Metabolites in Human Umbilical Vascular Endothelial CellsROCK2 mediates the proliferation of pulmonary arterial endothelial cells induced by hypoxia in the development of pulmonary arterial hypertension.Increase of 20-HETE synthase after brain ischemia in rats revealed by PET study with 11C-labeled 20-HETE synthase-specific inhibitor.Induction of angiotensin-converting enzyme and activation of the renin-angiotensin system contribute to 20-hydroxyeicosatetraenoic acid-mediated endothelial dysfunction.12-lipoxygenase and 12-hydroxyeicosatetraenoic acid regulate hypoxic angiogenesis and survival of pulmonary artery endothelial cells via PI3K/Akt pathway.Role of platelet-derived growth factor-BB (PDGF-BB) in human pulmonary artery smooth muscle cell proliferation.Detrimental Effects of Testosterone Addition to Estrogen Therapy Involve Cytochrome P-450-Induced 20-HETE Synthesis in Aorta of Ovariectomized Spontaneously Hypertensive Rat (SHR), a Model of Postmenopausal Hypertension.
P2860
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P2860
20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
20-HETE increases superoxide p ...... nary artery endothelial cells.
@en
20-HETE increases superoxide p ...... nary artery endothelial cells.
@nl
type
label
20-HETE increases superoxide p ...... nary artery endothelial cells.
@en
20-HETE increases superoxide p ...... nary artery endothelial cells.
@nl
prefLabel
20-HETE increases superoxide p ...... nary artery endothelial cells.
@en
20-HETE increases superoxide p ...... nary artery endothelial cells.
@nl
P2093
P2860
P50
P1476
20-HETE increases superoxide p ...... onary artery endothelial cells
@en
P2093
Daniel Harland
Debebe Gebremedhin
Elizabeth R Jacobs
Meetha Medhora
Siddam Anjaiah
Stephanie Gruenloh
Yuenmu Chen
P2860
P304
P356
10.1152/AJPLUNG.00278.2007
P577
2008-02-22T00:00:00Z