Role of L-arginine in the deficiency of nitric oxide and airway hyperreactivity after the allergen-induced early asthmatic reaction in guinea-pigs.
about
Arginase: a key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectivesArginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxationArginase strongly impairs neuronal nitric oxide-mediated airway smooth muscle relaxation in allergic asthmaRole of nitric oxide and superoxide in allergen-induced airway hyperreactivity after the late asthmatic reaction in guinea-pigsInflammatory cell distribution in guinea pig airways and its relationship to airway reactivityArginase and pulmonary diseasesGenetic polymorphisms in arginase I and II and childhood asthma and atopyNitric oxide and arginine dysregulation: a novel pathway to pulmonary hypertension in hemolytic disordersNitric oxide in health and disease of the respiratory system.The therapeutic potential of drugs targeting the arginase pathway in asthma.Competitive metabolism of L-arginine: arginase as a therapeutic target in asthma.Asymmetric dimethylarginine induces oxidative and nitrosative stress in murine lung epithelial cells.Nitric oxide in asthma physiopathology.Arginase and arginine dysregulation in asthma.Airway reactivity, inflammatory cell influx and nitric oxide in guinea-pig airways after lipopolysaccharide inhalation.Heparin normalizes allergen-induced nitric oxide deficiency and airway hyperresponsivenessModulation of cholinergic airway reactivity and nitric oxide production by endogenous arginase activity.Increased arginase activity underlies allergen-induced deficiency of cNOS-derived nitric oxide and airway hyperresponsiveness.l-Arginine administration attenuates airway inflammation by altering l-arginine metabolism in an NC/Nga mouse model of asthma.Nerve growth factor increases airway responses and decreases levels of exhaled nitric oxide during histamine challenge in an in vivo guinea-pig model.Decreased arginine bioavailability and increased serum arginase activity in asthma.Neurokinins and inflammatory cell iNOS expression in guinea pigs with chronic allergic airway inflammation.Arginase inhibition protects against allergen-induced airway obstruction, hyperresponsiveness, and inflammation.Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice.
P2860
Q24650052-DD2920D0-4BB8-42F4-A22B-C64805E1D086Q24804415-EA26CBDA-2DC5-4FEC-B800-C01A9FAF474FQ25255754-A37D3F69-FFE0-49BF-BB6F-1AA6F88ADDF6Q28345749-CCCC7B93-82EB-4BE6-AE15-B847B0335475Q28350179-98063211-2E3E-4DCD-9E63-07E7550C0B8AQ28385094-F2583E5B-E5A6-469C-8B8B-52930B06D1C1Q34574103-52973568-C650-486E-A032-150C15ED0C94Q35590733-B40D0D33-96FD-43E5-8962-F7394E828D17Q35842979-F286198E-BA0D-4FB4-8524-C18088679F74Q36268354-B6D911D6-9631-4734-9769-4DCE50D65490Q36682074-E5EFC8F5-9823-48B1-A98B-086E35BB4DF5Q40198573-A020BFBD-6CC5-4FC2-94EB-403D62893B57Q40850150-0DCEA2E6-7D28-495B-93A0-0C15AE64F73BQ41831572-CE20138B-2A7F-4227-9370-DFBD5DD1E344Q42037835-77EB43A9-9F74-494D-940B-3F303F4C1C52Q42079547-D4DCF3D6-C5F2-469F-BA7A-DF481B35CA37Q42116440-E3711E44-3166-44B0-A06F-9CBFA9D2D90DQ42126686-E794A93A-21DF-4142-9DF3-EC1C0500B776Q42739048-2A66DCB8-1FD1-4897-971A-D29709693ED5Q43782271-1A226852-FF11-48FF-A50B-E65476658F0FQ44834866-770E6FC8-A0AF-4FB6-81CD-B9278469FF26Q45173521-F04A8542-8D42-4C14-B7A2-80C869E2FE71Q46516143-C46DAEFC-6BBC-43A6-BAD4-C5B2FF0FC9ECQ47169088-CB721B7C-EA41-4976-BCA3-25DBAD0CC391
P2860
Role of L-arginine in the deficiency of nitric oxide and airway hyperreactivity after the allergen-induced early asthmatic reaction in guinea-pigs.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Role of L-arginine in the defi ...... matic reaction in guinea-pigs.
@en
Role of L-arginine in the defi ...... matic reaction in guinea-pigs.
@nl
type
label
Role of L-arginine in the defi ...... matic reaction in guinea-pigs.
@en
Role of L-arginine in the defi ...... matic reaction in guinea-pigs.
@nl
prefLabel
Role of L-arginine in the defi ...... matic reaction in guinea-pigs.
@en
Role of L-arginine in the defi ...... matic reaction in guinea-pigs.
@nl
P2093
P2860
P356
P1476
Role of L-arginine in the defi ...... matic reaction in guinea-pigs.
@en
P2093
P2860
P304
P356
10.1038/SJ.BJP.0702882
P407
P577
1999-11-01T00:00:00Z