The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations.
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HIV-1 Reverse Transcriptase (RT) Polymorphism 172K Suppresses the Effect of Clinically Relevant Drug Resistance Mutations to Both Nucleoside and Non-nucleoside RT InhibitorsThe renaissance of fixed dose combinations: CombivirN348I in reverse transcriptase provides a genetic pathway for HIV-1 to select thymidine analogue mutations and mutations antagonistic to thymidine analogue mutationsThe Role of Nucleotide Excision by Reverse Transcriptase in HIV Drug Resistance.Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition.HIV-1 reverse transcriptase and antiviral drug resistance. Part 2.The "Connection" Between HIV Drug Resistance and RNase HMutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistanceBaseline resistance to nucleoside reverse transcriptase inhibitors fails to predict virologic response to combination therapy in children (PACTG 338).Variations in reverse transcriptase and RNase H domain mutations in human immunodeficiency virus type 1 clinical isolates are associated with divergent phenotypic resistance to zidovudine.Connection subdomain mutations in HIV-1 subtype-C treatment-experienced patients enhance NRTI and NNRTI drug resistanceResistance to reverse transcriptase inhibitors used in the treatment and prevention of HIV-1 infection.The human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs.Thymidine analogue resistance suppression by V75I of HIV-1 reverse transcriptase: effects of substituting valine 75 on stavudine excision and discrimination.Molecular mechanism of HIV-1 resistance to 3'-azido-2',3'-dideoxyguanosine.Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase.Risk factors for selection of the L74I reverse transcriptase mutation in human immunodeficiency virus type 1-infected patients.A role of template cleavage in reduced excision of chain-terminating nucleotides by human immunodeficiency virus type 1 reverse transcriptase containing the M184V mutation.Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine.Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.Mechanism of resistance to GS-9148 conferred by the Q151L mutation in HIV-1 reverse transcriptase.Impact of human immunodeficiency virus type 1 reverse transcriptase inhibitor drug resistance mutation interactions on phenotypic susceptibility.
P2860
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P2860
The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
The L74V mutation in human imm ...... e analog resistance mutations.
@en
The L74V mutation in human imm ...... e analog resistance mutations.
@nl
type
label
The L74V mutation in human imm ...... e analog resistance mutations.
@en
The L74V mutation in human imm ...... e analog resistance mutations.
@nl
prefLabel
The L74V mutation in human imm ...... e analog resistance mutations.
@en
The L74V mutation in human imm ...... e analog resistance mutations.
@nl
P2093
P2860
P1476
The L74V mutation in human imm ...... e analog resistance mutations.
@en
P2093
Daniel R Kuritzkes
Luis R Miranda
Matthias Götte
P2860
P304
P356
10.1128/AAC.49.7.2648-2656.2005
P407
P577
2005-07-01T00:00:00Z