Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension.
about
Extending healthy life span--from yeast to humansLessons on longevity from budding yeastReplicative and chronological aging in Saccharomyces cerevisiae.The short-lived African turquoise killifish: an emerging experimental model for ageingDysregulated metabolism contributes to oncogenesisThe expanding role of yeast in cancer research and diagnosis: insights into the function of the oncosuppressors p53 and BRCA1/2The metabolism beyond programmed cell death in yeastThe protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae.Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation.Communications between Mitochondria, the Nucleus, Vacuoles, Peroxisomes, the Endoplasmic Reticulum, the Plasma Membrane, Lipid Droplets, and the Cytosol during Yeast Chronological AgingSlm35 links mitochondrial stress response and longevity through TOR signaling pathwayResveratrol inhibits protein translation in hepatic cellsyStreX: yeast stress expression databaseComparative analyses of time-course gene expression profiles of the long-lived sch9Delta mutant.Calorie restriction in mammals and simple model organisms.Calorie restriction and cancer prevention: metabolic and molecular mechanisms.Assessing chronological aging in bacteriaImpact papers on aging in 2009.With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in agingProlonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression.The nutrient stress-induced small GTPase Rab5 contributes to the activation of vesicle trafficking and vacuolar activity.Fasting and differential chemotherapy protection in patientsGlycerol extends lifespan of Brachionus manjavacas (Rotifera) and protects against stressorsTOR signaling never gets old: aging, longevity and TORC1 activity.Gis1 and Rph1 regulate glycerol and acetate metabolism in glucose depleted yeast cells.Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients.Fasting: molecular mechanisms and clinical applications.Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population.The general control nonderepressible-2 kinase mediates stress response and longevity induced by target of rapamycin inactivation in Caenorhabditis elegansGenome-wide screen for inositol auxotrophy in Saccharomyces cerevisiae implicates lipid metabolism in stress response signalingImpact of nutrient imbalance on wine alcoholic fermentations: nitrogen excess enhances yeast cell death in lipid-limited must.Identification of a lifespan extending mutation in the Schizosaccharomyces pombe cyclin gene clg1+ by direct selection of long-lived mutants.RasGrf1 deficiency delays aging in mice.Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling.Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response.Serine- and threonine/valine-dependent activation of PDK and Tor orthologs converge on Sch9 to promote aging.Distinct regulation of Maf1 for lifespan extension by Protein kinase A and Sch9The longevity of tor1Δ, sch9Δ, and ras2Δ mutants depends on actin dynamics in Saccharomyces cerevisiae.In Silico Docking of HNF-1a Receptor LigandsConserved role of medium acidification in chronological senescence of yeast and mammalian cells
P2860
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P2860
Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Tor1/Sch9-regulated carbon sou ...... iction in life span extension.
@en
Tor1/Sch9-regulated carbon sou ...... iction in life span extension.
@nl
type
label
Tor1/Sch9-regulated carbon sou ...... iction in life span extension.
@en
Tor1/Sch9-regulated carbon sou ...... iction in life span extension.
@nl
prefLabel
Tor1/Sch9-regulated carbon sou ...... iction in life span extension.
@en
Tor1/Sch9-regulated carbon sou ...... iction in life span extension.
@nl
P2093
P2860
P1433
P1476
Tor1/Sch9-regulated carbon sou ...... iction in life span extension.
@en
P2093
Federica Madia
Huanying Ge
Paola Fabrizio
Valter D Longo
P2860
P304
P356
10.1371/JOURNAL.PGEN.1000467
P577
2009-05-08T00:00:00Z