about
STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behavior.The N terminus of monoamine transporters is a lever required for the action of amphetaminesThe high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter.The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.Cell death mechanisms at the maternal-fetal interface: insights into the role of granulysin.Axonal targeting of the serotonin transporter in cultured rat dorsal raphe neurons is specified by SEC24C-dependent export from the endoplasmic reticulumNanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding SitesThe role of the conserved GXXXRXG motif in the expression and function of the human norepinephrine transporter.Functional significance of a highly conserved glutamate residue of the human noradrenaline transporter.Functional Rescue of a Misfolded Drosophila melanogaster Dopamine Transporter Mutant Associated with a Sleepless Phenotype by Pharmacological Chaperones.The cysteines of the extracellular loop are crucial for trafficking of human organic cation transporter 2 to the plasma membrane and are involved in oligomerization.Ca(2+)/calmodulin-dependent protein kinase IIα (αCaMKII) controls the activity of the dopamine transporter: implications for Angelman syndrome.Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates.Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24CThe N Terminus Specifies the Switch between Transport Modes of the Human Serotonin Transporter.A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter.A cytosolic relay of heat shock proteins HSP70-1A and HSP90β monitors the folding trajectory of the serotonin transporter.Corrigendum: STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behaviour.Calmodulin kinase II regulates amphetamine-induced reverse transport in dopamine and serotonin transporters.How does the carboxyl terminus assist folding and ER export of the serotonin transporter?Roles of transmembrane domain 2 and the first intracellular loop in human noradrenaline transporter function: pharmacological and SCAM analysis.Characterising the interaction between the COPII component SEC24C and the human serotonin transporter.An unfolding story: Small molecules remedy misfolded monoamine transporters.Pharmacochaperoning in a Drosophila model system rescues human dopamine transporter variants associated with infantile/juvenile parkinsonism.Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters.SLC6 Transporter Folding Diseases and Pharmacochaperoning.Ligand Selectivity among the Dopamine and Serotonin Transporters Specified by the Forward Binding Reaction.Investigation of the functional roles of the MELAL and GQXXRXG motifs of the human noradrenaline transporter using cysteine mutants.Several adaptor proteins promote intracellular localisation of the transporter MRP4/ABCC4 in platelets and haematopoietic cells.Comparison of the β-Adrenergic Receptor Antagonists Landiolol and Esmolol: Receptor Selectivity, Partial Agonism, and Pharmacochaperoning Actions.Differential regulation of amphetamine-induced serotonergic and dopaminergic efflux by syntaxin 1A.Concentrative ER export of the serotonin transporter relies exclusively on an interaction with Sec24C.Mutations in the amino-terminus impair amphetamine-induced efflux by inducing inward-facing conformations of the serotonin transporterStandardized phytotherapic extracts rescue anomalous locomotion and electrophysiological responses of TDP-43 Drosophila melanogaster model of ALSTruncations in the amino terminus reveal a region key to supporting amphetamine-induced efflux by the human serotonin transporterBig Lessons from Tiny Flies: as a Model to Explore Dysfunction of Dopaminergic and Serotonergic Neurotransmitter SystemsBig Lessons from Tiny Flies: Drosophila Melanogaster as a Model to Explore Dysfunction of Dopaminergic and Serotonergic Neurotransmitter SystemsWhen transporters fail to be transported: how to rescue folding-deficient SLC6 transportersClassical Radioligand Uptake and Binding Methods in Transporter Research: An Emphasis on the Monoamine Neurotransmitter TransportersFirst Trimester Pregnancy Decidual Natural Killer Cells Contain and Spontaneously Release High Quantities of Granulysin
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P50
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հետազոտող
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Sonja Sucic
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Sonja Sucic
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Sonja Sucic
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Sonja Sucic
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Sonja Sucic
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Sonja Sucic
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Sonja Sucic
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Sonja Sucic
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Sonja Sucic
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Sonja Sucic
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6507534934
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0000-0001-5136-8022