Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes. - Wikidata - wikimedia - TriplyDB

Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes.

Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes.

http://www.wikidata.org/entity/Q42136496

about

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis Role of areca nut induced JNK/ATF2/Jun axis in the activation of TGF-β pathway in precancerous Oral Submucous Fibrosis.Transforming growth factor activating kinase 1 regulates extracellular matrix degrading enzymes and pain-related molecule expression following tumor necrosis factor-α stimulation of synovial cells: an in vitro study.Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker.In vivo knockdown of TAK1 accelerates bone marrow proliferation/differentiation and induces systemic inflammation An essential role for TAK1 in the contact hypersensitivity response Suppression of collagen-induced arthritis in growth arrest and DNA damage-inducible protein 45β-deficient mice Decreased collagen-induced arthritis severity and adaptive immunity in MKK-6-deficient mice.Reactive oxygen species induce Cox-2 expression via TAK1 activation in synovial fibroblast cells.Regulation of inflammatory arthritis by the upstream kinase mitogen activated protein kinase kinase 7 in the c-Jun N-terminal kinase pathway A longitudinal genome-wide association study of anti-tumor necrosis factor response among Japanese patients with rheumatoid arthritis.Alpinetin suppresses proliferation of human hepatoma cells by the activation of MKK7 and elevates sensitization to cis-diammined dichloridoplatium.Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane.Mitogen-activated protein kinases as therapeutic targets in osteoarthritis.Synoviocyte innate immune responses: I. Differential regulation of interferon responses and the JNK pathway by MAPK kinases.Role of MAPK kinase 6 in arthritis: distinct mechanism of action in inflammation and cytokine expression.Dendritic cells for active anti-cancer immunotherapy: targeting activation pathways through genetic modification."Go upstream, young man": lessons learned from the p38 saga.Regulation of Transforming Growth Factor β-Activated Kinase Activation by Epigallocatechin-3-Gallate in Rheumatoid Arthritis Synovial Fibroblasts: Suppression of K(63) -Linked Autoubiquitination of Tumor Necrosis Factor Receptor-Associated Factor 6.MODULATING CO-STIMULATION DURING ANTIGEN PRESENTATION TO ENHANCE CANCER IMMUNOTHERAPY.Targeting lentiviral vectors for cancer immunotherapy.Transforming growth factor β activated kinase 1: a potential therapeutic target for rheumatic diseases.MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells.Kinetic analysis of synovial signalling and gene expression in animal models of arthritis.Adenovirus-Mediated Small Interfering RNA Targeting TAK1 Ameliorates Joint Inflammation with Collagen-Induced Arthritis in Mice.Ultraviolet irradiation can induce evasion of colon cancer cells from stimulation of epidermal growth factor.Supplemental N-acetylcysteine and other measures that boost intracellular glutathione can downregulate interleukin-1β signalling: a potential strategy for preventing cardiovascular events?Anti-proliferative Effect of C3 Exoenzyme in Fibroblasts is Mediated by c-Jun Phosphorylation.Pirfenidone suppresses MAPK signalling pathway to reverse epithelial-mesenchymal transition and renal fibrosis.Elucidation of molecular mechanisms underlying the protective effects of thymoquinone against rheumatoid arthritis.A cytokine protein-protein interaction network for identifying key molecules in rheumatoid arthritis.

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P2860

Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes.

http://www.wikidata.org/entity/Q42136496

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Regulation of the JNK pathway ...... matoid arthritis synoviocytes.

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Regulation of the JNK pathway ...... matoid arthritis synoviocytes.

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type

label

Regulation of the JNK pathway ...... matoid arthritis synoviocytes.

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Regulation of the JNK pathway ...... matoid arthritis synoviocytes.

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prefLabel

Regulation of the JNK pathway ...... matoid arthritis synoviocytes.

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Regulation of the JNK pathway ...... matoid arthritis synoviocytes.

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Arthritis Research and Therapy

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Regulation of the JNK pathway ...... matoid arthritis synoviocytes.

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David L Boyle

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Deepa R Hammaker

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Gary S Firestein

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Tomoyuki Inoue

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P2860

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.

Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol

TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kappaB

TAB3, a new binding partner of the protein kinase TAK1

Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation

MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells

Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling

Quantitative biomarker analysis of synovial gene expression by real-time PCR

Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors.

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10.1186/AR2215

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