Canonical Notch signaling is not necessary for prosensory induction in the mouse cochlea: insights from a conditional mutant of RBPjkappa.
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Early development of the vertebrate inner earBeyond generalized hair cells: molecular cues for hair cell typesMolecular mechanisms of inner ear developmentSegregating neural and mechanosensory fates in the developing ear: patterning, signaling, and transcriptional control.Conditional gene expression in the mouse inner ear using Cre-loxP.Sensory hair cell development and regeneration: similarities and differencesWhere hearing starts: the development of the mammalian cochleaCanonical Notch signaling plays an instructive role in auditory supporting cell development.The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organsInner ear development: building a spiral ganglion and an organ of Corti out of unspecified ectodermEvolution and development of the tetrapod auditory system: an organ of Corti-centric perspective.Sensory hair cell regeneration in the zebrafish lateral line.Cochlear progenitor number is controlled through mesenchymal FGF receptor signalingChanges in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochleaStem cell therapy for the inner ear: recent advances and future directions.Tympanic border cells are Wnt-responsive and can act as progenitors for postnatal mouse cochlear cells.Understanding the evolution and development of neurosensory transcription factors of the ear to enhance therapeutic translation.Fgf signaling regulates development and transdifferentiation of hair cells and supporting cells in the basilar papillaIn vivo visualization of Notch1 proteolysis reveals the heterogeneity of Notch1 signaling activity in the mouse cochlea.Concise review: Inner ear stem cells--an oxymoron, but why?Reconstruction of the mouse otocyst and early neuroblast lineage at single-cell resolution.Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear.Lineage tracing of Sox2-expressing progenitor cells in the mouse inner ear reveals a broad contribution to non-sensory tissues and insights into the origin of the organ of Corti.Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival.Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signalingIn vivo Notch reactivation in differentiating cochlear hair cells induces Sox2 and Prox1 expression but does not disrupt hair cell maturation.Overactivation of Notch1 signaling induces ectopic hair cells in the mouse inner ear in an age-dependent manner.Selection of cell fate in the organ of Corti involves the integration of Hes/Hey signaling at the Atoh1 promoter.The Atoh1-lineage gives rise to hair cells and supporting cells within the mammalian cochlea.Notch signaling during cell fate determination in the inner ear.Atoh1 directs hair cell differentiation and survival in the late embryonic mouse inner ear.Ectopic expression of activated notch or SOX2 reveals similar and unique roles in the development of the sensory cell progenitors in the mammalian inner ear.Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates.Patterning and cell fate in the inner ear: a case for Notch in the chicken embryo.Notch signaling in mammalian hair cell regeneration.Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.Expression of insulin-like growth factor binding proteins during mouse cochlear development.Notch Signaling in Development, Tissue Homeostasis, and Disease.Self-organized Notch dynamics generate stereotyped sensory organ patterns in Drosophila.NEUROG1 Regulates CDK2 to Promote Proliferation in Otic Progenitors.
P2860
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P2860
Canonical Notch signaling is not necessary for prosensory induction in the mouse cochlea: insights from a conditional mutant of RBPjkappa.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Canonical Notch signaling is n ...... nditional mutant of RBPjkappa.
@en
Canonical Notch signaling is n ...... nditional mutant of RBPjkappa.
@nl
type
label
Canonical Notch signaling is n ...... nditional mutant of RBPjkappa.
@en
Canonical Notch signaling is n ...... nditional mutant of RBPjkappa.
@nl
prefLabel
Canonical Notch signaling is n ...... nditional mutant of RBPjkappa.
@en
Canonical Notch signaling is n ...... nditional mutant of RBPjkappa.
@nl
P2093
P2860
P1476
Canonical Notch signaling is n ...... onditional mutant of RBPjkappa
@en
P2093
Martín L Basch
Neil Segil
Takahiro Ohyama
P2860
P304
P356
10.1523/JNEUROSCI.6671-10.2011
P407
P577
2011-06-01T00:00:00Z