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Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma

Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma

http://www.wikidata.org/entity/Q42142419

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Inhibition of Granulomatous Inflammation and Prophylactic Treatment of Schistosomiasis with a Combination of Edelfosine and Praziquantel Mantle cell lymphoma in the era of precision medicine-diagnosis, biomarkers and therapeutic agents Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review)Dysfunction of platelet-derived growth factor receptor α (PDGFRα) represses the production of oligodendrocytes from arylsulfatase A-deficient multipotential neural precursor cells Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression.Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways Edelfosine Promotes Apoptosis in Androgen-Deprived Prostate Tumors by Increasing ATF3 and Inhibiting Androgen Receptor Activity Molecular pathways: sterols and receptor signaling in cancer.Synergistic cytotoxicity of gemcitabine, clofarabine and edelfosine in lymphoma cell lines.Lipid rafts and raft-mediated supramolecular entities in the regulation of CD95 death receptor apoptotic signaling.Caenorhabditis elegans as a platform to study the mechanism of action of synthetic antitumor lipids The role of lipid raft translocation of prohibitin in regulation of Akt and Raf-protected apoptosis of HaCaT cells upon ultraviolet B irradiation.Mitochondria and lipid raft-located FOF1-ATP synthase as major therapeutic targets in the antileishmanial and anticancer activities of ether lipid edelfosine.The phenomenon of acquired resistance to metformin in breast cancer cells: The interaction of growth pathways and estrogen receptor signaling.Thymineless death in F10-treated AML cells occurs via lipid raft depletion and Fas/FasL co-localization in the plasma membrane with activation of the extrinsic apoptotic pathway.Characterisation of HRas local signal transduction networks using engineered site-specific exchange factors.Isolation of Lipid Rafts Through Discontinuous Sucrose Gradient Centrifugation and Fas/CD95 Death Receptor Localization in Raft Fractions.Design, synthesis and evaluation of alkylphosphocholine-gefitinib conjugates as multitarget anticancer agents.Synthesis of Bioconjugate Sesterterpenoids with Phospholipids and Polyunsaturated Fatty Acids.

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Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma

http://www.wikidata.org/entity/Q42142419

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma

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Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma

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type

label

Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma

@en

Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma

@nl

prefLabel

Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma

@en

Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma

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Blood Cancer Journal

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Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma

@en

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A Moros

http://www.w3.org/2001/XMLSchema#string

C Gajate

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D Colomer

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F Mollinedo

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G Roué

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J de la Iglesia-Vicente

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M Reis-Sobreiro

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P2860

Improvement of Overall Survival in Advanced Stage Mantle Cell Lymphoma

PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer

mTOR: from growth signal integration to cancer, diabetes and ageing

Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics.

Lipid rafts and signal transduction

Regulation of cell death protease caspase-9 by phosphorylation

Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy

Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells

Perifosine, a novel alkylphospholipid, inhibits protein kinase B activation

Intracellular triggering of Fas, independently of FasL, as a new mechanism of antitumor ether lipid-induced apoptosis.

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e118

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10.1038/BCJ.2013.15

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3

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