Intracellular triggering of Fas, independently of FasL, as a new mechanism of antitumor ether lipid-induced apoptosis.
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Edelfosine-induced metabolic changes in cancer cells that precede the overproduction of reactive oxygen species and apoptosisInhibition of Granulomatous Inflammation and Prophylactic Treatment of Schistosomiasis with a Combination of Edelfosine and PraziquantelExogenous ether lipids predominantly target mitochondriaInvolvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cellsIn vitro and in vivo efficacy of ether lipid edelfosine against Leishmania spp. and SbV-resistant parasitesSynthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the mitochondrial death pathway.Lipid raft-targeted therapy in multiple myeloma.Autoimmune lymphoproliferative syndrome: molecular basis of disease and clinical phenotype.Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions.Human TMEM30a promotes uptake of antitumor and bioactive choline phospholipids into mammalian cellsInvolvement of lipid rafts in the localization and dysfunction effect of the antitumor ether phospholipid edelfosine in mitochondria.Cell membranes and apoptosis: role of cardiolipin, phosphatidylcholine, and anticancer lipid analogues.Oncolytic vesicular stomatitis virus induces apoptosis via signaling through PKR, Fas, and Daxx.Endoplasmic reticulum targeting in Ewing's sarcoma by the alkylphospholipid analog edelfosineDrug uptake, lipid rafts, and vesicle trafficking modulate resistance to an anticancer lysophosphatidylcholine analogue in yeastYC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathwayLipid rafts and clusters of apoptotic signaling molecule-enriched rafts in cancer therapy.Lipid rafts and raft-mediated supramolecular entities in the regulation of CD95 death receptor apoptotic signaling.Caenorhabditis elegans as a platform to study the mechanism of action of synthetic antitumor lipidsSignaling active CD95 receptor molecules trigger co-translocation of inactive CD95 molecules into lipid raftsAntitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulum.The alkylphospholipid, perifosine, radiosensitizes prostate cancer cells both in vitro and in vivo.Molecular ordering of the initial signaling events of CD95.Fas/CD95 down-regulation in lymphoma cells through acquired alkyllysophospholipid resistance: partial role of associated sphingomyelin deficiency.Mitochondria and lipid raft-located FOF1-ATP synthase as major therapeutic targets in the antileishmanial and anticancer activities of ether lipid edelfosine.Miltefosine (hexadecylphosphocholine) inhibits cytochrome c oxidase in Leishmania donovani promastigotes.TRAIL-induced apoptosis in U-1242 MG glioma cells.ET-18-O-CH3-induced apoptosis is causally linked to COX-2 upregulation in H-ras transformed human breast epithelial cells.On the mechanism of alkylphosphocholine (APC)-induced apoptosis in tumour cells.Bacterial cupredoxin azurin as an inducer of apoptosis and regression in human breast cancer.Necroptosis is associated with low procaspase-8 and active RIPK1 and -3 in human glioma cells.Alteration of plasma membrane organization by an anticancer lysophosphatidylcholine analogue induces intracellular acidification and internalization of plasma membrane transporters in yeast.Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fas-enriched rafts in selective tumor cell apoptosisLipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphomaDifferential cytostatic and apoptotic effects of ecteinascidin-743 in cancer cells. Transcription-dependent cell cycle arrest and transcription-independent JNK and mitochondrial mediated apoptosis.Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an ATM-dependent manner.Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells.Effect of anti-tumor ether lipids on ordered domains in model membranesDifferential Targets and Subcellular Localization of Antitumor Alkyl-lysophospholipid in LeukemicVersusSolid Tumor Cells
P2860
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P2860
Intracellular triggering of Fas, independently of FasL, as a new mechanism of antitumor ether lipid-induced apoptosis.
description
2000 nî lūn-bûn
@nan
2000 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մարտին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Intracellular triggering of Fa ...... ether lipid-induced apoptosis.
@ast
Intracellular triggering of Fa ...... ether lipid-induced apoptosis.
@en
type
label
Intracellular triggering of Fa ...... ether lipid-induced apoptosis.
@ast
Intracellular triggering of Fa ...... ether lipid-induced apoptosis.
@en
prefLabel
Intracellular triggering of Fa ...... ether lipid-induced apoptosis.
@ast
Intracellular triggering of Fa ...... ether lipid-induced apoptosis.
@en
P2093
P2860
P1476
Intracellular triggering of Fa ...... ether lipid-induced apoptosis.
@en
P2093
F Mollinedo
G Alvarez-Noves
M Modolell
R I Fonteriz
Y Alvarez-Rodriguez
P2860
P304
P356
10.1002/(SICI)1097-0215(20000301)85:5<674::AID-IJC13>3.0.CO;2-Z
P577
2000-03-01T00:00:00Z