Down-regulation of Rac GTPase-activating protein OCRL1 causes aberrant activation of Rac1 in osteoarthritis development. - Wikidata - wikimedia - TriplyDB

Down-regulation of Rac GTPase-activating protein OCRL1 causes aberrant activation of Rac1 in osteoarthritis development.

Down-regulation of Rac GTPase-activating protein OCRL1 causes aberrant activation of Rac1 in osteoarthritis development.

http://www.wikidata.org/entity/Q42145534

about

The oculocerebrorenal syndrome of Lowe: an update Rac1 in human diseases: The therapeutic potential of targeting Rac1 signaling regulatory mechanisms.Intra-articular Delivery of Antago-miR-483-5p Inhibits Osteoarthritis by Modulating Matrilin 3 and Tissue Inhibitor of Metalloproteinase 2.Wogonoside inhibits IL-1β induced catabolism and hypertrophy in mouse chondrocyte and ameliorates murine osteoarthritis.Subchondral mesenchymal stem cells from osteoarthritic knees display high osteogenic differentiation capacity through microRNA-29a regulation of HDAC4.Kidney-differentiated cells derived from Lowe Syndrome patient's iPSCs show ciliogenesis defects and Six2 retention at the Golgi complex.Recent Insights into the Contribution of the Changing Hypertrophic Chondrocyte Phenotype in the Development and Progression of Osteoarthritis.Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells

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Down-regulation of Rac GTPase-activating protein OCRL1 causes aberrant activation of Rac1 in osteoarthritis development.

http://www.wikidata.org/entity/Q42145534

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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name

Down-regulation of Rac GTPase- ...... in osteoarthritis development.

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Down-regulation of Rac GTPase- ...... in osteoarthritis development.

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Down-regulation of Rac GTPase- ...... in osteoarthritis development.

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Down-regulation of Rac GTPase- ...... in osteoarthritis development.

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Down-regulation of Rac GTPase- ...... in osteoarthritis development.

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Down-regulation of Rac GTPase- ...... in osteoarthritis development.

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Down-regulation of Rac GTPase- ...... in osteoarthritis development.

@en

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Hong Wei Ouyang

http://www.w3.org/2001/XMLSchema#string

Hu Hu

http://www.w3.org/2001/XMLSchema#string

Huanhuan Liu

http://www.w3.org/2001/XMLSchema#string

Jun Dai

http://www.w3.org/2001/XMLSchema#string

Shouan Zhu

http://www.w3.org/2001/XMLSchema#string

Xiaoxia Cong

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Yan Wu

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Yishan Chen

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P2860

Lowe syndrome protein OCRL1 interacts with Rac GTPase in the trans-Golgi network

The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase

Dent Disease with mutations in OCRL1

Lowe syndrome protein OCRL1 interacts with clathrin and regulates protein trafficking between endosomes and the trans-Golgi network

A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway

Vav2 is required for cell spreading

The cellular and physiological functions of the Lowe syndrome protein OCRL1

Rab proteins as membrane organizers

Phosphoinositides in cell regulation and membrane dynamics

Phosphatidylinositol-4-phosphate 5-kinase localized on the plasma membrane is essential for yeast cell morphogenesis.

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2154-2163

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10.1002/ART.39174

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8

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67

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