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Functional specialization of islet dendritic cell subsets

Functional specialization of islet dendritic cell subsets

http://www.wikidata.org/entity/Q42149313

about

Dendritic cell subsets in type 1 diabetes: friend or foe?An evolving autoimmune microenvironment regulates the quality of effector T cell restimulation and function Cognate antigen engagement on parenchymal cells stimulates CD8+ T cell proliferation in situ.The central role of antigen presentation in islets of Langerhans in autoimmune diabetes The gene expression profile of CD11c+ CD8α- dendritic cells in the pre-diabetic pancreas of the NOD mouse.A minor subset of Batf3-dependent antigen-presenting cells in islets of Langerhans is essential for the development of autoimmune diabetes.Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse Effect of dietary gluten on dendritic cells and innate immune subsets in BALB/c and NOD mice Pathogenic mechanisms in type 1 diabetes: the islet is both target and driver of disease.Association of proinflammatory cytokines and islet resident leucocytes with islet dysfunction in type 2 diabetes Immunological pathways to β-cell damage in Type 1 diabetes.The Mononuclear Phagocyte System in Organ Transplantation.Cutting Edge: Origins, Recruitment, and Regulation of CD11c+ Cells in Inflamed Islets of Autoimmune Diabetes Mice.Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity.

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Functional specialization of islet dendritic cell subsets

http://www.wikidata.org/entity/Q42149313

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Functional specialization of islet dendritic cell subsets

@en

Functional specialization of islet dendritic cell subsets

@nl

type

label

Functional specialization of islet dendritic cell subsets

@en

Functional specialization of islet dendritic cell subsets

@nl

prefLabel

Functional specialization of islet dendritic cell subsets

@en

Functional specialization of islet dendritic cell subsets

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JIMMUNOL.1103725

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Journal of Immunology

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Functional specialization of islet dendritic cell subsets

@en

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Florent Ginhoux

http://www.w3.org/2001/XMLSchema#string

Gwendalyn J Randolph

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Jiangnan Xu

http://www.w3.org/2001/XMLSchema#string

Jonathan S Bromberg

http://www.w3.org/2001/XMLSchema#string

Miriam Merad

http://www.w3.org/2001/XMLSchema#string

Na Yin

http://www.w3.org/2001/XMLSchema#string

Yaozhong Ding

http://www.w3.org/2001/XMLSchema#string

P2860

Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells

Dendritic cells and the control of immunity

Aire regulates negative selection of organ-specific T cells

Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors

Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells.

CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

Differential antigen processing by dendritic cell subsets in vivo

Tolerogenic dendritic cells

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

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4921-4930

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