Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells.
about
Present status of clinical deployment of glucokinase activatorsDPP-4 inhibition improves early mortality, β cell function, and adipose tissue inflammation in db/db mice fed a diet containing sucrose and linoleic acid.Safety, tolerability, pharmacokinetics, and pharmacodynamics of novel glucokinase activator HMS5552: results from a first-in-human single ascending dose study.Par-4/NF-κB Mediates the Apoptosis of Islet β Cells Induced by Glucolipotoxicity.IRS1 deficiency protects β-cells against ER stress-induced apoptosis by modulating sXBP-1 stability and protein translation.Proteomic and phosphoproteomic analysis of renal cortex in a salt-load rat model of advanced kidney damage.The endoplasmic reticulum stress/autophagy pathway is involved in cholesterol-induced pancreatic β-cell injury.Compound 19e, a Novel Glucokinase Activator, Protects against Cytokine-Induced Beta-Cell Apoptosis in INS-1 Cells.PAR-4: a possible new target for age-related disease.Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation.Novel factors modulating human β-cell proliferation.Metabolic recovery of lipodystrophy, liver steatosis, and pancreatic β cell proliferation after the withdrawal of OSI-906.Selective and sequential loss of transcriptional factors: A hallmark of β-cell failure in type 2 diabetes?Identification of the matricellular protein Fibulin-5 as a target molecule of glucokinase-mediated calcineurin/NFAT signaling in pancreatic islets.Glucose- or insulin resistance-mediated β-cell replication: PKCζ integrates the proliferative signalingMisfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes.TERT and Akt Are Involved in the Par-4-Dependent Apoptosis of Islet Cells in Type 2 Diabetes
P2860
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P2860
Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells.
@en
Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells.
@nl
type
label
Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells.
@en
Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells.
@nl
prefLabel
Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells.
@en
Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells.
@nl
P2093
P2860
P356
P1433
P1476
Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells.
@en
P2093
Eri Sakamoto
Hideaki Inoue
Kazuki Orime
Kazuki Tajima
Mitsuyo Kaji
Naoto Kubota
Takashi Kadowaki
Yasuo Terauchi
Yu Togashi
P2860
P304
P356
10.2337/DB13-0052
P407
P577
2013-06-25T00:00:00Z