The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction.
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Structural Insights into High Density Lipoprotein: Old Models and New FactsNew insights into the determination of HDL structure by apolipoproteins: Thematic review series: high density lipoprotein structure, function, and metabolismHaptoglobin genotype and its role in determining heme-iron mediated vascular diseaseApolipoprotein A-I: insights from redox proteomics for its role in neurodegenerationDouble Superhelix Model of High Density LipoproteinCryo-EM structure of the ribosome–SecYE complex in the membrane environmentThe Structure of Dimeric Apolipoprotein A-IV and Its Mechanism of Self-AssociationSequence conservation of apolipoprotein A-I affords novel insights into HDL structure-function3-nitrotyrosine modified proteins in atherosclerosisResidual Cardiovascular Risk in Chronic Kidney Disease: Role of High-density LipoproteinMaturation of high-density lipoproteins.Dynamics of activation of lecithin:cholesterol acyltransferase by apolipoprotein A-IABCA1 dimer-monomer interconversion during HDL generation revealed by single-molecule imaging.MD simulations suggest important surface differences between reconstituted and circulating spherical HDL.Mass spectrometric determination of apolipoprotein molecular stoichiometry in reconstituted high density lipoprotein particles.Oxidative risk for atherothrombotic cardiovascular disease.Dysfunctional HDL as a diagnostic and therapeutic targetCongruency between biophysical data from multiple platforms and molecular dynamics simulation of the double-super helix model of nascent high-density lipoprotein.Site-specific nitration of apolipoprotein A-I at tyrosine 166 is both abundant within human atherosclerotic plaque and dysfunctional.Structures of discoidal high density lipoproteins: a combined computational-experimental approachMyeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoproteinDisruption of the C-terminal helix by single amino acid deletion is directly responsible for impaired cholesterol efflux ability of apolipoprotein A-I Nichinan.Immunochemical Approach for Monitoring of Structural Transition of ApoA-I upon HDL Formation Using Novel Monoclonal AntibodiesElevated plasma albumin and apolipoprotein A-I oxidation under suboptimal specimen storage conditions.Activation of lecithin:cholesterol acyltransferase by HDL ApoA-I central helices.High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis.Conformation of dimeric apolipoprotein A-I milano on recombinant lipoprotein particles.Myeloperoxidase, inflammation, and dysfunctional high-density lipoproteinMorphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy.Assessment of the validity of the double superhelix model for reconstituted high density lipoproteins: a combined computational-experimental approach.Structure of apolipoprotein A-I N terminus on nascent high density lipoproteins.Detergent/nanodisc screening for high-resolution NMR studies of an integral membrane protein containing a cytoplasmic domain.The low resolution structure of ApoA1 in spherical high density lipoprotein revealed by small angle neutron scattering.Atomistic MD simulation reveals the mechanism by which CETP penetrates into HDL enabling lipid transfer from HDL to CETPDistinct HDL subclasses present similar intrinsic susceptibility to oxidation by HOCl.Apolipoprotein A-I structural organization in high-density lipoproteins isolated from human plasma."Sticky" and "promiscuous", the yin and yang of apolipoprotein A-I termini in discoidal high-density lipoproteins: a combined computational-experimental approach.HDL from apoA1 transgenic mice expressing the 4WF isoform is resistant to oxidative loss of functionConformational transitions in the membrane scaffold protein of phospholipid bilayer nanodiscsRole of Conserved Proline Residues in Human Apolipoprotein A-IV Structure and Function.
P2860
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P2860
The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
The refined structure of nasce ...... le maturation and dysfunction.
@en
The refined structure of nasce ...... le maturation and dysfunction.
@nl
type
label
The refined structure of nasce ...... le maturation and dysfunction.
@en
The refined structure of nasce ...... le maturation and dysfunction.
@nl
prefLabel
The refined structure of nasce ...... le maturation and dysfunction.
@en
The refined structure of nasce ...... le maturation and dysfunction.
@nl
P2093
P2860
P356
P1476
The refined structure of nasce ...... le maturation and dysfunction.
@en
P2093
Jacinto M Shy
John S Parks
Jonathan D Smith
Lemin Zheng
Matthew A Wagner
Stanley L Hazen
Valentin Gogonea
Zhiping Wu
P2860
P2888
P304
P356
10.1038/NSMB1284
P577
2007-08-05T00:00:00Z
P5875
P6179
1053003435