Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins
about
Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutationsA novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells.Modulation of Immune Cell Functions by the E3 Ligase Cbl-b.Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene.Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy.VAV1-Cre mediated hematopoietic deletion of CBL and CBL-B leads to JMML-like aggressive early-neonatal myeloproliferative disease.Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis.Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.
P2860
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P2860
Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
@zh-cn
name
Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins
@en
Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins
@nl
type
label
Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins
@en
Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins
@nl
prefLabel
Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins
@en
Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins
@nl
P2093
P2860
P356
P1476
Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins
@en
P2093
Amarnath Natarajan
Gloria E O Borgstahl
Gulzar Ahmad
Hamid Band
Mayumi Naramura
Nick Palermo
Scott Nadeau
Vimla Band
P2860
P356
10.4172/2161-1009.S6-001
P478
P577
2012-07-01T00:00:00Z