ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration.
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The Role of Crk Adaptor Proteins in T-Cell Adhesion and MigrationRetention of CXCR4 in the endoplasmic reticulum blocks dissemination of a T cell hybridomaT cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.The oncogenic 70Z Cbl mutation blocks the phosphotyrosine binding domain-dependent negative regulation of ZAP-70 by c-Cbl in Jurkat T cells.CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse.Novel molecular diagnostic and therapeutic targets in chronic lymphocytic leukaemia.LFA-1 Engagement Triggers T Cell Polarization at the HIV-1 Virological Synapse.LFA-1-dependent Ca2+ entry following suboptimal T cell receptor triggering proceeds without mobilization of intracellular Ca2+.CXCR3-mediated T-cell chemotaxis involves ZAP-70 and is regulated by signalling through the T-cell receptor.SDF-1 has costimulatory effects on human T cells: possible involvement of MAPK (ERK2) activation.Regulation of cytokine signaling by B cell antigen receptor and CD40-controlled expression of heparan sulfate proteoglycans.The N-terminal SH2 domains of Syk and ZAP-70 mediate phosphotyrosine-independent binding to integrin beta cytoplasmic domains.Jak kinase activity is required for lymphoma invasion and metastasis.Hypomorphic mutation of ZAP70 in human results in a late onset immunodeficiency and no autoimmunity.Analysis of dynamic tyrosine phosphoproteome in LFA-1 triggered migrating T-cells.
P2860
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P2860
ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration.
@en
ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration.
@nl
type
label
ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration.
@en
ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration.
@nl
prefLabel
ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration.
@en
ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration.
@nl
P2093
P2860
P356
P1476
ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration.
@en
P2093
I Van Kouteren-Cobzaru
Y M Wijnands
P2860
P304
P356
10.1083/JCB.142.5.1371
P407
P577
1998-09-01T00:00:00Z