1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide.
about
Salvianolic acid B attenuates toxin-induced neuronal damage via Nrf2-dependent glial cells-mediated protective activity in Parkinson's disease modelsUrate and its transgenic depletion modulate neuronal vulnerability in a cellular model of Parkinson's disease.Neuroprotective Effects of Alpha-Mangostin on MPP(+)-Induced Apoptotic Cell Death in Neuroblastoma SH-SY5Y Cells.Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage.Chronic exposure to nitric oxide alters the free iron pool in endothelial cells: role of mitochondrial respiratory complexes and heat shock proteins.Mitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and H₂O₂.Low Levels of Prohibitin in Substantia Nigra Makes Dopaminergic Neurons Vulnerable in Parkinson's Disease.Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cellsThiol-redox signaling, dopaminergic cell death, and Parkinson's diseaseThe role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during agingCatalytic antioxidants to treat amyotropic lateral sclerosis.Chelation of mitochondrial iron prevents seizure-induced mitochondrial dysfunction and neuronal injury.Glutathione depletion in immortalized midbrain-derived dopaminergic neurons results in increases in the labile iron pool: implications for Parkinson's disease.Antioxidant gene therapy against neuronal cell death.HPLC-based monitoring of products formed from hydroethidine-based fluorogenic probes--the ultimate approach for intra- and extracellular superoxide detection.MicroRNA-181a Regulates Apoptosis and Autophagy Process in Parkinson's Disease by Inhibiting p38 Mitogen-Activated Protein Kinase (MAPK)/c-Jun N-Terminal Kinases (JNK) Signaling Pathways.α-Synuclein and mitochondrial bioenergetics regulate tetrahydrobiopterin levels in a human dopaminergic model of Parkinson disease.Metabolic Dysfunction in Parkinson's Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism.Alterations in bioenergetic function induced by Parkinson's disease mimetic compounds: lack of correlation with superoxide generation.DJ-1 modulates the expression of Cu/Zn-superoxide dismutase-1 through the Erk1/2-Elk1 pathway in neuroprotection.Death-associated protein kinase as a sensor of mitochondrial membrane potential: role of lysosome in mitochondrial toxin-induced cell death.Alpha-synuclein up-regulation and aggregation during MPP+-induced apoptosis in neuroblastoma cells: intermediacy of transferrin receptor iron and hydrogen peroxide.Glucose Levels in Culture Medium Determine Cell Death Mode in MPP(+)-treated Dopaminergic Neuronal Cells.Δ⁹-tetrahydrocannabinol (Δ⁹-THC) exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease.The homocysteine-inducible endoplasmic reticulum stress protein counteracts calcium store depletion and induction of CCAAT enhancer-binding protein homologous protein in a neurotoxin model of Parkinson disease.1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide.Dopamine-derived dopaminochrome promotes H(2)O(2) release at mitochondrial complex I: stimulation by rotenone, control by Ca(2+), and relevance to Parkinson disease.The unintended mitochondrial uncoupling effects of the FDA-approved anti-helminth drug nitazoxanide mitigates experimental parkinsonism in mice.Inhibition of the cdk5/p25 fragment formation may explain the antiapoptotic effects of melatonin in an experimental model of Parkinson's disease.Plant-Derived Natural Products for Parkinson's Disease Therapy.Malate transported from chloroplast to mitochondrion triggers production of ROS and PCD in Arabidopsis thaliana.Characteristics of the mitochondrial and cellular uptake of MPP+, as probed by the fluorescent mimic, 4'I-MPP
P2860
Q28540349-ED436F9E-AB97-4309-9817-3690BB8BEE2FQ34273978-F2B014A4-03CE-407F-9818-E60687C7D8F3Q34672936-071A93BC-9B66-4909-937D-AEAFF90CF3A3Q34987124-EDC2FA9B-08D4-4B94-8134-FD2D1D4FC625Q35123040-A9B8AF1D-35BC-4459-B615-AB38208A129BQ35240549-0060D76A-88E5-42CC-9953-1C8594DFB616Q36243568-58A126EF-B660-491F-B168-B9E01DCA4339Q36275187-CD977875-F8FE-4AD1-B5D7-B24B8FBAF2CFQ36326535-3827FECA-94BA-49A7-88F1-4AA2F5E67661Q36449196-DD9D5032-0A5E-4FE8-AED1-6766D16EE1DAQ36623068-272B1802-A2C1-431D-BA4F-D8B3EA5747A3Q37036598-4451702B-0AFE-4E99-957E-7A1BFD0432DDQ37178356-2DB46870-4F6C-4205-B14A-087165965C10Q37647941-EB2B0980-BA36-4DF4-BDE2-45FE3378E750Q38106521-418D9A6A-DE35-4E54-B343-0C67317C4857Q38709419-A0ABC585-0422-40C1-92BF-5F5A31FB6E61Q39073685-0E65F5F3-E2A9-4D25-AE00-53C35786ECC1Q39199926-0929FC13-0980-4E28-B8E2-9F754F274EFCQ39329410-C900BC38-3C63-45D8-B41A-88E633A9C47DQ39499315-73FB1867-B6E0-45AB-B97C-29CCD0E7A469Q40387553-64574CC1-50CE-4C20-923F-0601AF7FA760Q40595894-5A1B324D-3973-4438-99CC-56BBDBF738EFQ42161145-E50A1B2F-9C9A-426E-96AA-4385BFE7F0D5Q42500348-8F543E05-05D1-4AFE-9FB1-F29FB60C2E5AQ43095684-E1604746-CCE8-443E-B860-64EA611471E8Q44748873-097A3316-3F3E-417B-ACD7-45CB9BA12550Q45264842-4FC56A70-1E35-462A-8E34-344A18E2C9A3Q46322674-A99F2E5F-58FE-4469-BAA4-A504D4DAECCAQ46961856-6951E410-0AD0-4B5B-A389-CA6985EC8E47Q51800931-48D93D05-A989-4018-B481-90AAD1E4379FQ52355314-11302A88-CB82-4161-9076-E4BB33E3C3D1Q58715913-893DB575-1B2C-433E-A9C1-A83E13EE8FB9
P2860
1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
1-Methyl-4-phenylpyridinium (M ...... nt iron and hydrogen peroxide.
@en
1-Methyl-4-phenylpyridinium
@nl
type
label
1-Methyl-4-phenylpyridinium (M ...... nt iron and hydrogen peroxide.
@en
1-Methyl-4-phenylpyridinium
@nl
prefLabel
1-Methyl-4-phenylpyridinium (M ...... nt iron and hydrogen peroxide.
@en
1-Methyl-4-phenylpyridinium
@nl
P2093
P2860
P356
P1433
P1476
1-Methyl-4-phenylpyridinium (M ...... nt iron and hydrogen peroxide.
@en
P2093
B Kalyanaraman
Cecilia J Hillard
Shasi V Kalivendi
Sonya Cunningham
Srigiridhar Kotamraju
Tiesong Shang
P2860
P304
P356
10.1042/BJ20021525
P407
P577
2003-04-01T00:00:00Z