Conjugation site heterogeneity causes variable electrostatic properties in Fc conjugates. - Wikidata - wikimedia - TriplyDB

Conjugation site heterogeneity causes variable electrostatic properties in Fc conjugates.

Conjugation site heterogeneity causes variable electrostatic properties in Fc conjugates.

http://www.wikidata.org/entity/Q42174344

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Linkers Having a Crucial Role in Antibody-Drug Conjugates Antibody-drug conjugates as novel anti-cancer chemotherapeutics Novel Anti-Nicotine Vaccine Using a Trimeric Coiled-Coil Hapten Carrier Antibody drug conjugates: design and selection of linker, payload and conjugation chemistry Stability analysis of an inline peptide-based conjugate for metal delivery: nickel(II)-claMP Tag epidermal growth factor as a model system.Effects of localized interactions and surface properties on stability of protein-based therapeutics.Computational Construction of Antibody-Drug Conjugates Using Surface Lysines as the Antibody Conjugation Site and a Non-cleavable Linker Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate.In-depth structural characterization of Kadcyla® (ado-trastuzumab emtansine) and its biosimilar candidate.Chemically programmed antibodies.Antibody-Drug Conjugates: Design, Formulation and Physicochemical Stability.Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates.Detection and quantitation of succinimide in intact protein via hydrazine trapping and chemical derivatization.Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates Current challenges in peptide-based drug discovery.Challenges and new frontiers in analytical characterization of antibody-drug conjugates.An anti-EGFR × cotinine bispecific antibody complexed with cotinine-conjugated duocarmycin inhibits growth of EGFR-positive cancer cells with KRAS mutations.

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P2860

Conjugation site heterogeneity causes variable electrostatic properties in Fc conjugates.

http://www.wikidata.org/entity/Q42174344

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2013 nî lūn-bûn

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name

Conjugation site heterogeneity causes variable electrostatic properties in Fc conjugates.

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Conjugation site heterogeneity causes variable electrostatic properties in Fc conjugates.

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type

label

Conjugation site heterogeneity causes variable electrostatic properties in Fc conjugates.

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Conjugation site heterogeneity causes variable electrostatic properties in Fc conjugates.

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prefLabel

Conjugation site heterogeneity causes variable electrostatic properties in Fc conjugates.

@en

Conjugation site heterogeneity causes variable electrostatic properties in Fc conjugates.

@nl

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Bioconjugate Chemistry

P1476

Conjugation site heterogeneity causes variable electrostatic properties in Fc conjugates

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P2093

Janet L Wolfe

http://www.w3.org/2001/XMLSchema#string

Nicholas J Boylan

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Robert J Proos

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Thomas J Tolbert

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Wen Zhou

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P2860

Charge variants in IgG1: Isolation, characterization, in vitro binding properties and pharmacokinetics in rats

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

Electrostatic strengths of salt bridges in thermophilic and mesophilic glutamate dehydrogenase monomers.

Formulation considerations for proteins susceptible to asparagine deamidation and aspartate isomerization.

Cloning and disruption of the PpURA5 gene and construction of a set of integration vectors for the stable genetic modification of Pichia pastoris.

Enhancing antibody Fc heterodimer formation through electrostatic steering effects: applications to bispecific molecules and monovalent IgG.

Heterogeneity of monoclonal antibodies revealed by charge-sensitive methods.

Antibody-drug conjugates: linking cytotoxic payloads to monoclonal antibodies.

Impact of linker and conjugation chemistry on antigen binding, Fc receptor binding and thermal stability of model antibody-drug conjugates

Carboxyl pK(a) values, ion pairs, hydrogen bonding, and the pH-dependence of folding the hyperthermophile proteins Sac7d and Sso7d

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1008-1016

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scholarly article

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10.1021/BC4000564

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6

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24

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Jennifer S Laurence

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2013-05-31T00:00:00Z

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23777335

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3713463

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